{"id":7675,"date":"2024-05-03T11:16:32","date_gmt":"2024-05-03T09:16:32","guid":{"rendered":"http:\/\/54.217.166.153\/o\/arcnl\/"},"modified":"2024-05-03T11:19:32","modified_gmt":"2024-05-03T09:19:32","slug":"arcnl","status":"publish","type":"portfolio","link":"https:\/\/mimir.nu\/en\/o\/arcnl\/","title":{"rendered":"ARCNL"},"content":{"rendered":"  \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_heading-2028e3f858a37872d6637318f2430d6e\">\n#top .av-special-heading.av-av_heading-2028e3f858a37872d6637318f2430d6e{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-av_heading-2028e3f858a37872d6637318f2430d6e .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-av_heading-2028e3f858a37872d6637318f2430d6e .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-av_heading-2028e3f858a37872d6637318f2430d6e av-special-heading-h3'><h3 class='av-special-heading-tag '  itemprop=\"headline\"  >Jobs posted by AMOLF<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n  <section  class='av_textblock_section av-av_textblock-0366cc7376be6c9e82a3e9cc8987b64f '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>    Mimir provides the automated job management of jobs on job boards for <a href=\"https:\/\/amolf.nl\/\">AMOLF<\/a>.<\/p>\n<\/div><\/section>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_heading-ec4bf286390e57c0f372b4510908f00a\">\n#top .av-special-heading.av-av_heading-ec4bf286390e57c0f372b4510908f00a{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-av_heading-ec4bf286390e57c0f372b4510908f00a .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-av_heading-ec4bf286390e57c0f372b4510908f00a .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-av_heading-ec4bf286390e57c0f372b4510908f00a av-special-heading-h4'><h4 class='av-special-heading-tag '  itemprop=\"headline\"  >Latest jobs<\/h4><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n  \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_two_third-61be9178410eaaa3f443d4723cbbaeb0\">\n.flex_column.av-av_two_third-61be9178410eaaa3f443d4723cbbaeb0{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-av_two_third-61be9178410eaaa3f443d4723cbbaeb0 av_two_third first flex_column_div av-zero-column-padding  '     ><section  class='av_textblock_section av-av_textblock-0366cc7376be6c9e82a3e9cc8987b64f '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><h5 class=\"no-translation\">PhD student: Single-molecule biophysics of ribosome cooperation<\/h5>\n<p class=\"no-translation\"><strong>Work Activities<\/strong><br \/><strong>Summary -<\/strong> In this project, you will perform innovative (bio)physics experiments to elucidate the dynamic action of individual ribosomes. The key methodologies are optical tweezers, single-molecule fluorescence, as well as selective ribosome profiling \u2013 an exciting new RNA sequencing method. Working in the Tans biophysics lab @ AMOLF Amsterdam, you will visualize the real-time translation activity of ribosomes, how multiple ribosomes work together, detect the folding of individual polypeptide chains, and show how chaperones guide this process. You will work in an international team, with other groups specialized in ribosome profiling and cryo-EM techniques. The aim is to elucidate the fundamental mechanisms that underlie the correct and erroneous production of new proteins.<\/p>\n<p><strong>Questions -<\/strong> According to textbooks, ribosomes work individually to produce proteins. However, recent insights from our lab and others show multiple ribosomes cooperate as they translate mRNA. This cooperation may well be essential to produce multi-protein complexes faithfully. In our group, we aim to elucidate the highly diverse and broad implications. Questions we are interested in include: Do ribosomes synchronize their translation activity in real-time, like a sequence of cars in traffic? Are mRNA secondary structures and\/or direct interactions between ribosomes involved? How do the two (or more) protein chains synthesized by these multiple ribosomes fold together to form protein complexes? How many ribosomes cooperate together? Can we see cooperation between ribosomes that translate different RNA messages? Given the novelty of these fundamental questions in this rapidly expanding field, you will have a unique chance to address them first.<\/p>\n<p><strong>Approach -<\/strong> You will directly follow the unknown dynamics of ribosome translation, protein folding and assembly, and chaperone guidance. This is enabled using optical tweezers combined with single-molecule fluorescence, which detect changes in individual molecules at nanometer and millisecond resolution. In collaboration with our partners, you will also use selective ribosome profiling \u2013 an RNA sequencing method that provides high-level data across the genome an <em>in-vivo<\/em>. This first look may reveal a host of unexpected phenomena. You will develop new experimental schemes, Use cutting-edge single-molecule fluorescence and manipulation methods, Adapt existing biochemical protocols, Analyze the complex temporal data, formulation of new models, And explain your findings in high-level scientific papers.<\/p>\n<p><strong>International team -<\/strong> You will be part of a collaboration with leading groups at Heidelberg University and the ETH in Zurich, which use novel sequencing and cryo-EM methods. By working within this motivated group of young scientists, you will obtain a unique training, understanding and skill set in this expanding field. By integrating these approaches, you will provide insights of unprecedented detail, spanning from the cellular to the atomic level, from <em>in vivo<\/em> to <em>in vitro<\/em>, from genome-wide patterns to molecular mechanisms, and from bacteria to human cells.<\/p>\n<p>Image left show ribosome (blue, orange) that synthesized protein chain (yellow) by translating the RNA message (red). Image right shows dynamic ribosome interactions.<\/p>\n<p><strong>Qualifications<\/strong><br \/>We have a number of positions available (PhD and PD). We are looking for outstanding experimental physicists or chemists with an interest in single-molecule techniques, ambition to make breakthrough findings, programming skills to handle complex data, and who thrive in a diverse, collaborative, and supportive environment. Excellent verbal and written English skills are essential. You meet the requirements for an MSc-degree to ensure eligibility for a Dutch PhD examination.<\/p>\n<p><strong>Work environment<\/strong><br \/>AMOLF is a part of NWO-I and initiate and performs leading fundamental research on the physics of complex forms of matter, and to create new functional materials, in partnership with academia and industry. The institute is located at Amsterdam Science Park and currently employs about 140 researchers and 80 support employees. <a href=\"http:\/\/www.amolf.nl\">www.amolf.nl<\/a><\/p>\n<p><strong>Our group -<\/strong> We form a lively and close-knit research group of about 10 PhD students and postdocs, which work together in small teams on various projects in a highly supportive and social atmosphere that extends to the other research groups at the AMOLF institute, which is housed in a modern building in the east of Amsterdam. The Tans group at the AMOLF institute Amsterdam has been at the forefront of studying chaperone-guided protein folding using optical tweezers. This technique allows one to mechanically manipulate individual proteins, and hence follow the movements and folding steps as they fold. We have shown striking sequences of molecular events that underlie chaperone functions, which are invisible with other methods.<\/p>\n<p><a href=\"https:\/\/www.sandertanslab.nl\/\">https:\/\/www.sandertanslab.nl<\/a><\/p>\n<p><a href=\"https:\/\/amolf.nl\/research-groups\/biophysics\">https:\/\/amolf.nl\/research-groups\/biophysics<\/a><\/p>\n<p><strong>Working conditions<\/strong><\/p>\n<ul>\n<li>The working atmosphere at the institute is largely determined by young, enthusiastic, mostly foreign employees. Communication is informal and runs through short lines of communication.<\/li>\n<li>The position is intended as full-time (40 hours \/ week, 12 months \/ year) appointment in the service of the Netherlands Foundation of Scientific Research Institutes (NWO-I) for the duration of four years<\/li>\n<li>The starting salary is 2.781 Euro\u2019s gross per month and a <a href=\"https:\/\/www.nwo-i.nl\/en\/working-at-nwo-i\/informationforapplicants\/\">range of employment benefits<\/a>.<\/li>\n<li>After successful completion of the PhD research a PhD degree will be granted at Delft University of Technology.<\/li>\n<li>Several courses are offered, specially developed for PhD-students.<\/li>\n<li>Funding is available to attend regularly international conferences.<\/li>\n<li>AMOLF assists any new foreign PhD-student with housing and visa applications and compensates their transport costs and furnishing expenses.<\/li>\n<\/ul>\n<p><strong>More information?<\/strong><br \/>https:\/\/www.sandertanslab.nl<\/p>\n<p><strong>Application<\/strong><br \/>You can respond to this vacancy online via the button below.<\/p>\n<p>Please annex your:<\/p>\n<ul>\n<li>Resume;<\/li>\n<li>Motivation on why you want to join the group (max. 1 page).<\/li>\n<\/ul>\n<p>It is important to us to know why you want to join our team. Hence, we will only consider your application if it contains your motivation letter.<\/p>\n<p>Applications will be evaluated on a rolling basis and as soon as an excellent match is made, the position will be filled.<\/p>\n<p><em>Online screening may be part of the selection.<\/em><\/p>\n<p><strong>Diversity code<\/strong><br \/>AMOLF is highly committed to an inclusive and diverse work environment: we want to develop talent and creativity by bringing together people from different backgrounds and cultures. We recruit and select on the basis of competencies and talents. We strongly encourage anyone with the right qualifications to apply for the vacancy, regardless of age, gender, origin, sexual orientation or physical ability.<\/p>\n<p>AMOLF has won the NNV Diversity Award 2022, which is awarded every two years by the Netherlands Physical Society for demonstrating the most successful implementation of equality, diversity and inclusion (EDI).<\/p>\n<p><em><strong>Commercial activities in response to this ad are not appreciated.<\/strong><\/em><\/p>\n<p>\n<\/div><\/section><\/div>\n  \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_one_third-0aa7055fe62c3622faec82866afbaeb2\">\n.flex_column.av-av_one_third-0aa7055fe62c3622faec82866afbaeb2{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-av_one_third-0aa7055fe62c3622faec82866afbaeb2 av_one_third flex_column_div av-zero-column-padding  '     ><div  class='togglecontainer av-av_toggle_container-d03efdf7de8d15029af4a4ccb5448be7' ><div class='taglist'><div class=\"tag-tab\"><a href=\"#\" data-tag=\"{All}\" class=\"activeFilter\">All<\/a><span class='tag-seperator'>\/<\/span><\/div><div class=\"tag-tab\"><a href=\"#\" data-tag=\"{Applications}\" class=\"\">Applications<\/a><span class='tag-seperator'>\/<\/span><\/div><\/div>\n              <section class='av_toggle_section av-av_toggle-b8ee849c6cf1d254dc71ee5adae1b3d7'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{All} {Applications} \"  ><p id='toggle-toggle-id-1' data-fake-id='#toggle-id-1' class='toggler  activeTitle av-title-above '  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-1' data-slide-speed=\"200\" data-title=\"AcademicTransfer\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: AcademicTransfer\" data-aria_expanded=\"Click to collapse: AcademicTransfer\">AcademicTransfer<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/p><div id='toggle-id-1' aria-labelledby='toggle-toggle-id-1' role='region' class='toggle_wrap  active_tc av-title-above' style='display:block;' ><div class='toggle_content invers-color '  itemprop=\"text\" ><p>          \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_font_icon-68df07e82f9aa7e9ca8086cf07328158\">\n.av_font_icon.av-av_font_icon-68df07e82f9aa7e9ca8086cf07328158 .av-icon-char{\nfont-size:12px;\nline-height:12px;\n}\n<\/style>\n<span  class='av_font_icon av-av_font_icon-68df07e82f9aa7e9ca8086cf07328158 avia_animate_when_visible av-icon-style- avia-icon-pos-left avia-iconfont avia-font-entypo-fontello av-no-color avia-icon-animate'><span class='av-icon-char' data-av_icon='\ue82d' data-av_iconfont='entypo-fontello' aria-hidden=\"true\" ><\/span><\/span> 21 applications<br \/>\n          \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_font_icon-2ad3e02231965e18a13969aa2ae9da8b\">\n.av_font_icon.av-av_font_icon-2ad3e02231965e18a13969aa2ae9da8b .av-icon-char{\nfont-size:12px;\nline-height:12px;\n}\n<\/style>\n<span  class='av_font_icon av-av_font_icon-2ad3e02231965e18a13969aa2ae9da8b avia_animate_when_visible av-icon-style- avia-icon-pos-left avia-iconfont avia-font-entypo-fontello av-no-color avia-icon-animate'><span class='av-icon-char' data-av_icon='\ue80b' data-av_iconfont='entypo-fontello' aria-hidden=\"true\" ><\/span><\/span> 0 views                  <\/p>\n<\/div><\/div><\/div><\/section>\n          <\/div><\/div>\n  <br style=\"clear: both\">\n  <span style=\"margin-top: 20px; float: right\">25-04-2026<\/span>\n  <span style=\"margin-top: 20px; font-weight: bold; float: left\">AMOLF<\/span>\n  <hr>  \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_two_third-61be9178410eaaa3f443d4723cbbaeb0\">\n.flex_column.av-av_two_third-61be9178410eaaa3f443d4723cbbaeb0{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-av_two_third-61be9178410eaaa3f443d4723cbbaeb0 av_two_third first flex_column_div av-zero-column-padding  '     ><section  class='av_textblock_section av-av_textblock-0366cc7376be6c9e82a3e9cc8987b64f '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><h5 class=\"no-translation\">PhD student: Single-molecule biophysics of ribosome cooperation<\/h5>\n<p class=\"no-translation\"><strong>Work Activities<\/strong><br \/><strong>Summary -<\/strong> In this project, you will perform innovative (bio)physics experiments to elucidate the dynamic action of individual ribosomes. The key methodologies are optical tweezers, single-molecule fluorescence, as well as selective ribosome profiling \u2013 an exciting new RNA sequencing method. Working in the Tans biophysics lab @ AMOLF Amsterdam, you will visualize the real-time translation activity of ribosomes, how multiple ribosomes work together, detect the folding of individual polypeptide chains, and show how chaperones guide this process. You will work in an international team, with other groups specialized in ribosome profiling and cryo-EM techniques. The aim is to elucidate the fundamental mechanisms that underlie the correct and erroneous production of new proteins.<\/p>\n<p><strong>Questions -<\/strong> According to textbooks, ribosomes work individually to produce proteins. However, recent insights from our lab and others show multiple ribosomes cooperate as they translate mRNA. This cooperation may well be essential to produce multi-protein complexes faithfully. In our group, we aim to elucidate the highly diverse and broad implications. Questions we are interested in include: Do ribosomes synchronize their translation activity in real-time, like a sequence of cars in traffic? Are mRNA secondary structures and\/or direct interactions between ribosomes involved? How do the two (or more) protein chains synthesized by these multiple ribosomes fold together to form protein complexes? How many ribosomes cooperate together? Can we see cooperation between ribosomes that translate different RNA messages? Given the novelty of these fundamental questions in this rapidly expanding field, you will have a unique chance to address them first.<\/p>\n<p><strong>Approach -<\/strong> You will directly follow the unknown dynamics of ribosome translation, protein folding and assembly, and chaperone guidance. This is enabled using optical tweezers combined with single-molecule fluorescence, which detect changes in individual molecules at nanometer and millisecond resolution. In collaboration with our partners, you will also use selective ribosome profiling \u2013 an RNA sequencing method that provides high-level data across the genome an <em>in-vivo<\/em>. This first look may reveal a host of unexpected phenomena. You will develop new experimental schemes, Use cutting-edge single-molecule fluorescence and manipulation methods, Adapt existing biochemical protocols, Analyze the complex temporal data, formulation of new models, And explain your findings in high-level scientific papers.<\/p>\n<p><strong>International team -<\/strong> You will be part of a collaboration with leading groups at Heidelberg University and the ETH in Zurich, which use novel sequencing and cryo-EM methods. By working within this motivated group of young scientists, you will obtain a unique training, understanding and skill set in this expanding field. By integrating these approaches, you will provide insights of unprecedented detail, spanning from the cellular to the atomic level, from <em>in vivo<\/em> to <em>in vitro<\/em>, from genome-wide patterns to molecular mechanisms, and from bacteria to human cells.<\/p>\n<p>Image left show ribosome (blue, orange) that synthesized protein chain (yellow) by translating the RNA message (red). Image right shows dynamic ribosome interactions.<\/p>\n<p><strong>Qualifications<\/strong><br \/>We have a number of positions available (PhD and PD). We are looking for outstanding experimental physicists or chemists with an interest in single-molecule techniques, ambition to make breakthrough findings, programming skills to handle complex data, and who thrive in a diverse, collaborative, and supportive environment. Excellent verbal and written English skills are essential. You meet the requirements for an MSc-degree to ensure eligibility for a Dutch PhD examination.<\/p>\n<p><strong>Work environment<\/strong><br \/>AMOLF is a part of NWO-I and initiate and performs leading fundamental research on the physics of complex forms of matter, and to create new functional materials, in partnership with academia and industry. The institute is located at Amsterdam Science Park and currently employs about 140 researchers and 80 support employees. <a href=\"http:\/\/www.amolf.nl\">www.amolf.nl<\/a><\/p>\n<p><strong>Our group -<\/strong> We form a lively and close-knit research group of about 10 PhD students and postdocs, which work together in small teams on various projects in a highly supportive and social atmosphere that extends to the other research groups at the AMOLF institute, which is housed in a modern building in the east of Amsterdam. The Tans group at the AMOLF institute Amsterdam has been at the forefront of studying chaperone-guided protein folding using optical tweezers. This technique allows one to mechanically manipulate individual proteins, and hence follow the movements and folding steps as they fold. We have shown striking sequences of molecular events that underlie chaperone functions, which are invisible with other methods.<\/p>\n<p><a href=\"https:\/\/www.sandertanslab.nl\/\">https:\/\/www.sandertanslab.nl<\/a><\/p>\n<p><a href=\"https:\/\/amolf.nl\/research-groups\/biophysics\">https:\/\/amolf.nl\/research-groups\/biophysics<\/a><\/p>\n<p><strong>Working conditions<\/strong><\/p>\n<ul>\n<li>The working atmosphere at the institute is largely determined by young, enthusiastic, mostly foreign employees. Communication is informal and runs through short lines of communication.<\/li>\n<li>The position is intended as full-time (40 hours \/ week, 12 months \/ year) appointment in the service of the Netherlands Foundation of Scientific Research Institutes (NWO-I) for the duration of four years<\/li>\n<li>The starting salary is 2.781 Euro\u2019s gross per month and a <a href=\"https:\/\/www.nwo-i.nl\/en\/working-at-nwo-i\/informationforapplicants\/\">range of employment benefits<\/a>.<\/li>\n<li>After successful completion of the PhD research a PhD degree will be granted at Delft University of Technology.<\/li>\n<li>Several courses are offered, specially developed for PhD-students.<\/li>\n<li>Funding is available to attend regularly international conferences.<\/li>\n<li>AMOLF assists any new foreign PhD-student with housing and visa applications and compensates their transport costs and furnishing expenses.<\/li>\n<\/ul>\n<p><strong>More information?<\/strong><br \/>https:\/\/www.sandertanslab.nl<\/p>\n<p><strong>Application<\/strong><br \/>You can respond to this vacancy online via the button below.<\/p>\n<p>Please annex your:<\/p>\n<ul>\n<li>Resume;<\/li>\n<li>Motivation on why you want to join the group (max. 1 page).<\/li>\n<\/ul>\n<p>It is important to us to know why you want to join our team. Hence, we will only consider your application if it contains your motivation letter.<\/p>\n<p>Applications will be evaluated on a rolling basis and as soon as an excellent match is made, the position will be filled.<\/p>\n<p><em>Online screening may be part of the selection.<\/em><\/p>\n<p><strong>Diversity code<\/strong><br \/>AMOLF is highly committed to an inclusive and diverse work environment: we want to develop talent and creativity by bringing together people from different backgrounds and cultures. We recruit and select on the basis of competencies and talents. We strongly encourage anyone with the right qualifications to apply for the vacancy, regardless of age, gender, origin, sexual orientation or physical ability.<\/p>\n<p>AMOLF has won the NNV Diversity Award 2022, which is awarded every two years by the Netherlands Physical Society for demonstrating the most successful implementation of equality, diversity and inclusion (EDI).<\/p>\n<p><em><strong>Commercial activities in response to this ad are not appreciated.<\/strong><\/em><\/p>\n<p>\n<\/div><\/section><\/div>\n  \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_one_third-0aa7055fe62c3622faec82866afbaeb2\">\n.flex_column.av-av_one_third-0aa7055fe62c3622faec82866afbaeb2{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-av_one_third-0aa7055fe62c3622faec82866afbaeb2 av_one_third flex_column_div av-zero-column-padding  '     ><div  class='togglecontainer av-av_toggle_container-d03efdf7de8d15029af4a4ccb5448be7' ><div class='taglist'><div class=\"tag-tab\"><a href=\"#\" data-tag=\"{All}\" class=\"activeFilter\">All<\/a><span class='tag-seperator'>\/<\/span><\/div><div class=\"tag-tab\"><a href=\"#\" data-tag=\"{Applications}\" class=\"\">Applications<\/a><span class='tag-seperator'>\/<\/span><\/div><div class=\"tag-tab\"><a href=\"#\" data-tag=\"{Views}\" class=\"\">Views<\/a><span class='tag-seperator'>\/<\/span><\/div><\/div>\n              <section class='av_toggle_section av-av_toggle-c97acb92fabb1e65090e2ef688c101dd'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{All} {Applications} {Views} \"  ><p id='toggle-toggle-id-2' data-fake-id='#toggle-id-2' class='toggler  activeTitle av-title-above '  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-2' data-slide-speed=\"200\" data-title=\"Academic Positions\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: Academic Positions\" data-aria_expanded=\"Click to collapse: Academic Positions\">Academic Positions<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/p><div id='toggle-id-2' aria-labelledby='toggle-toggle-id-2' role='region' class='toggle_wrap  active_tc av-title-above' style='display:block;' ><div class='toggle_content invers-color '  itemprop=\"text\" ><p>          \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_font_icon-68df07e82f9aa7e9ca8086cf07328158\">\n.av_font_icon.av-av_font_icon-68df07e82f9aa7e9ca8086cf07328158 .av-icon-char{\nfont-size:12px;\nline-height:12px;\n}\n<\/style>\n<span  class='av_font_icon av-av_font_icon-68df07e82f9aa7e9ca8086cf07328158 avia_animate_when_visible av-icon-style- avia-icon-pos-left avia-iconfont avia-font-entypo-fontello av-no-color avia-icon-animate'><span class='av-icon-char' data-av_icon='\ue82d' data-av_iconfont='entypo-fontello' aria-hidden=\"true\" ><\/span><\/span> 28 applications<br \/>\n          \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_font_icon-2ad3e02231965e18a13969aa2ae9da8b\">\n.av_font_icon.av-av_font_icon-2ad3e02231965e18a13969aa2ae9da8b .av-icon-char{\nfont-size:12px;\nline-height:12px;\n}\n<\/style>\n<span  class='av_font_icon av-av_font_icon-2ad3e02231965e18a13969aa2ae9da8b avia_animate_when_visible av-icon-style- avia-icon-pos-left avia-iconfont avia-font-entypo-fontello av-no-color avia-icon-animate'><span class='av-icon-char' data-av_icon='\ue80b' data-av_iconfont='entypo-fontello' aria-hidden=\"true\" ><\/span><\/span> 212 views                  <\/p>\n<\/div><\/div><\/div><\/section>\n          <\/div><\/div>\n  <br style=\"clear: both\">\n  <span style=\"margin-top: 20px; float: right\">25-04-2026<\/span>\n  <span style=\"margin-top: 20px; font-weight: bold; float: left\">AMOLF<\/span>\n  <hr>  \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_two_third-61be9178410eaaa3f443d4723cbbaeb0\">\n.flex_column.av-av_two_third-61be9178410eaaa3f443d4723cbbaeb0{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-av_two_third-61be9178410eaaa3f443d4723cbbaeb0 av_two_third first flex_column_div av-zero-column-padding  '     ><section  class='av_textblock_section av-av_textblock-0366cc7376be6c9e82a3e9cc8987b64f '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><h5 class=\"no-translation\">Postdoc: Revealing ribosomes using single-molecule and RNA sequencing<\/h5>\n<p class=\"no-translation\"><strong>Work Activities<\/strong><br \/><strong>Summary -<\/strong> In this project, you will perform innovative (bio)physics experiments to elucidate the dynamic action of individual ribosomes - specifically their interactions within polysomes. The key methodologies are optical tweezers, single-molecule fluorescence, as well as selective ribosome profiling \u2013 an exciting new RNA sequencing method. Working in the Tans biophysics lab @ AMOLF Amsterdam, you will visualize the real-time translation activity of ribosomes, how multiple ribosomes work together, detect the folding of individual polypeptide chains, and show how chaperones guide this process. You will work in an international team, with other groups specialized in ribosome profiling and cryo-EM techniques. The aim is to elucidate the fundamental mechanisms that underlie the correct and erroneous production of new proteins.<\/p>\n<p><strong>Questions -<\/strong> According to textbooks, ribosomes work individually to produce proteins. However, recent insights from our lab and others show multiple ribosomes cooperate as they translate mRNA. This cooperation within larger \u2018polysomes\u2019 may well be essential to produce multi-protein complexes faithfully. In our group, we aim to elucidate the highly diverse and broad implications. Questions we are interested in include: Do ribosomes synchronize their translation activity in real-time, like a sequence of cars in traffic? Are mRNA secondary structures and\/or direct interactions between ribosomes involved? How do the two (or more) protein chains synthesized by these multiple ribosomes fold together to form protein complexes? How many ribosomes cooperate together? Can we see cooperation between ribosomes that translate different RNA messages? Given the novelty of these fundamental questions in this rapidly expanding field, you will have a unique chance to address them first.<\/p>\n<p><strong>Approach -<\/strong> You will directly follow the unknown dynamics of ribosome translation, protein folding and assembly, and chaperone guidance. This is enabled using optical tweezers combined with single-molecule fluorescence, which detect changes in individual molecules at nanometer and millisecond resolution. In collaboration with our partners, you will also use selective ribosome profiling \u2013 an RNA sequencing method that provides high-level data across the genome an <em>in-vivo<\/em>. This first look may reveal a host of unexpected phenomena. You will develop new experimental schemes, Use cutting-edge single-molecule fluorescence and manipulation methods, Adapt existing biochemical protocols, Analyze the complex temporal data, formulation of new models, And explain your findings in high-level scientific papers.<\/p>\n<p><strong>International team -<\/strong> You will be part of a collaboration with leading groups at Heidelberg University and the ETH in Zurich, which use novel sequencing and cryo-EM methods. By working within this motivated group of young scientists, you will obtain a unique training, understanding and skill set in this expanding field. By integrating these approaches, you will provide insights of unprecedented detail, spanning from the cellular to the atomic level, from <em>in vivo<\/em> to <em>in vitro<\/em>, from genome-wide patterns to molecular mechanisms, and from bacteria to human cells.<\/p>\n<p>Image left show ribosome (blue, orange) that synthesized protein chain (yellow) by translating the RNA message (red). Image right shows dynamic ribosome interactions.<\/p>\n<p><strong>Qualifications<\/strong><br \/>We have a number of positions available (PhD and PD). We are looking for outstanding experimental physicists or chemists with an interest in single-molecule techniques, ambition to make breakthrough findings, programming skills to handle complex data, and who thrive in a diverse, collaborative, and supportive environment. Excellent verbal and written English skills are essential.<\/p>\n<p><strong>Work environment<\/strong><br \/>AMOLF is a part of NWO-I and initiate and performs leading fundamental research on the physics of complex forms of matter, and to create new functional materials, in partnership with academia and industry. The institute is located at Amsterdam Science Park and currently employs about 140 researchers and 80 support employees. <a href=\"http:\/\/www.amolf.nl\">www.amolf.nl<\/a><\/p>\n<p><strong>Our group -<\/strong> We form a lively and close-knit research group of about 10 PhD students and postdocs, which work together in small teams on various projects in a highly supportive and social atmosphere that extends to the other research groups at the AMOLF institute, which is housed in a modern building in the east of Amsterdam. The Tans group at the AMOLF institute Amsterdam has been at the forefront of studying chaperone-guided protein folding using optical tweezers. This technique allows one to mechanically manipulate individual proteins, and hence follow the movements and folding steps as they fold. We have shown striking sequences of molecular events that underlie chaperone functions, which are invisible with other methods.<\/p>\n<p><a href=\"https:\/\/www.sandertanslab.nl\/\">https:\/\/www.sandertanslab.nl<\/a><\/p>\n<p><a href=\"https:\/\/amolf.nl\/research-groups\/biophysics\">https:\/\/amolf.nl\/research-groups\/biophysics<\/a><\/p>\n<p><strong>Working conditions<\/strong><\/p>\n<ul>\n<li>The working atmosphere at the institute is largely determined by young, enthusiastic, mostly foreign employees. Communication is informal and runs through short lines of communication.<\/li>\n<li>The position is intended as full-time (40 hours \/ week, 12 months \/ year) appointment in the service of the Netherlands Foundation of Scientific Research Institutes (NWO-I) for the duration of four years<\/li>\n<li>Funding is available to attend regularly international conferences.<\/li>\n<li>AMOLF assists any new foreign researcher with housing and visa applications and compensates their transport costs and furnishing expenses.<\/li>\n<\/ul>\n<p><strong>More information?<\/strong><br \/>https:\/\/www.sandertanslab.nl<\/p>\n<p><strong>Application<\/strong><br \/>You can respond to this vacancy online via the button below.<\/p>\n<p>Please annex your:<\/p>\n<ul>\n<li>Resume;<\/li>\n<li>Motivation on why you want to join the group (max. 1 page).<\/li>\n<\/ul>\n<p>It is important to us to know why you want to join our team. Hence, we will only consider your application if it contains your motivation letter.<\/p>\n<p>Applications will be evaluated on a rolling basis and as soon as an excellent match is made, the position will be filled.<\/p>\n<p><em>Online screening may be part of the selection.<\/em><\/p>\n<p><strong>Diversity code<\/strong><br \/>AMOLF is highly committed to an inclusive and diverse work environment: we want to develop talent and creativity by bringing together people from different backgrounds and cultures. We recruit and select on the basis of competencies and talents. We strongly encourage anyone with the right qualifications to apply for the vacancy, regardless of age, gender, origin, sexual orientation or physical ability.<\/p>\n<p>AMOLF has won the NNV Diversity Award 2022, which is awarded every two years by the Netherlands Physical Society for demonstrating the most successful implementation of equality, diversity and inclusion (EDI).<\/p>\n<p><em><strong>Commercial activities in response to this ad are not appreciated.<\/strong><\/em><\/p>\n<p>\n<\/div><\/section><\/div>\n  \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_one_third-0aa7055fe62c3622faec82866afbaeb2\">\n.flex_column.av-av_one_third-0aa7055fe62c3622faec82866afbaeb2{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-av_one_third-0aa7055fe62c3622faec82866afbaeb2 av_one_third flex_column_div av-zero-column-padding  '     ><div  class='togglecontainer av-av_toggle_container-d03efdf7de8d15029af4a4ccb5448be7' ><div class='taglist'><div class=\"tag-tab\"><a href=\"#\" data-tag=\"{All}\" class=\"activeFilter\">All<\/a><span class='tag-seperator'>\/<\/span><\/div><div class=\"tag-tab\"><a href=\"#\" data-tag=\"{Applications}\" class=\"\">Applications<\/a><span class='tag-seperator'>\/<\/span><\/div><\/div>\n              <section class='av_toggle_section av-av_toggle-b8ee849c6cf1d254dc71ee5adae1b3d7'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{All} {Applications} \"  ><p id='toggle-toggle-id-3' data-fake-id='#toggle-id-3' class='toggler  activeTitle av-title-above '  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-3' data-slide-speed=\"200\" data-title=\"AcademicTransfer\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: AcademicTransfer\" data-aria_expanded=\"Click to collapse: AcademicTransfer\">AcademicTransfer<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/p><div id='toggle-id-3' aria-labelledby='toggle-toggle-id-3' role='region' class='toggle_wrap  active_tc av-title-above' style='display:block;' ><div class='toggle_content invers-color '  itemprop=\"text\" ><p>          \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_font_icon-68df07e82f9aa7e9ca8086cf07328158\">\n.av_font_icon.av-av_font_icon-68df07e82f9aa7e9ca8086cf07328158 .av-icon-char{\nfont-size:12px;\nline-height:12px;\n}\n<\/style>\n<span  class='av_font_icon av-av_font_icon-68df07e82f9aa7e9ca8086cf07328158 avia_animate_when_visible av-icon-style- avia-icon-pos-left avia-iconfont avia-font-entypo-fontello av-no-color avia-icon-animate'><span class='av-icon-char' data-av_icon='\ue82d' data-av_iconfont='entypo-fontello' aria-hidden=\"true\" ><\/span><\/span> 11 applications<br \/>\n          \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_font_icon-2ad3e02231965e18a13969aa2ae9da8b\">\n.av_font_icon.av-av_font_icon-2ad3e02231965e18a13969aa2ae9da8b .av-icon-char{\nfont-size:12px;\nline-height:12px;\n}\n<\/style>\n<span  class='av_font_icon av-av_font_icon-2ad3e02231965e18a13969aa2ae9da8b avia_animate_when_visible av-icon-style- avia-icon-pos-left avia-iconfont avia-font-entypo-fontello av-no-color avia-icon-animate'><span class='av-icon-char' data-av_icon='\ue80b' data-av_iconfont='entypo-fontello' aria-hidden=\"true\" ><\/span><\/span> 0 views                  <\/p>\n<\/div><\/div><\/div><\/section>\n          <\/div><\/div>\n  <br style=\"clear: both\">\n  <span style=\"margin-top: 20px; float: right\">25-04-2026<\/span>\n  <span style=\"margin-top: 20px; font-weight: bold; float: left\">AMOLF<\/span>\n  <hr>  \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_two_third-61be9178410eaaa3f443d4723cbbaeb0\">\n.flex_column.av-av_two_third-61be9178410eaaa3f443d4723cbbaeb0{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-av_two_third-61be9178410eaaa3f443d4723cbbaeb0 av_two_third first flex_column_div av-zero-column-padding  '     ><section  class='av_textblock_section av-av_textblock-0366cc7376be6c9e82a3e9cc8987b64f '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><h5 class=\"no-translation\">Postdoc: Revealing ribosomes using single-molecule and RNA sequencing<\/h5>\n<p class=\"no-translation\"><strong>Work Activities<\/strong><br \/><strong>Summary -<\/strong> In this project, you will perform innovative (bio)physics experiments to elucidate the dynamic action of individual ribosomes - specifically their interactions within polysomes. The key methodologies are optical tweezers, single-molecule fluorescence, as well as selective ribosome profiling \u2013 an exciting new RNA sequencing method. Working in the Tans biophysics lab @ AMOLF Amsterdam, you will visualize the real-time translation activity of ribosomes, how multiple ribosomes work together, detect the folding of individual polypeptide chains, and show how chaperones guide this process. You will work in an international team, with other groups specialized in ribosome profiling and cryo-EM techniques. The aim is to elucidate the fundamental mechanisms that underlie the correct and erroneous production of new proteins.<\/p>\n<p><strong>Questions -<\/strong> According to textbooks, ribosomes work individually to produce proteins. However, recent insights from our lab and others show multiple ribosomes cooperate as they translate mRNA. This cooperation within larger \u2018polysomes\u2019 may well be essential to produce multi-protein complexes faithfully. In our group, we aim to elucidate the highly diverse and broad implications. Questions we are interested in include: Do ribosomes synchronize their translation activity in real-time, like a sequence of cars in traffic? Are mRNA secondary structures and\/or direct interactions between ribosomes involved? How do the two (or more) protein chains synthesized by these multiple ribosomes fold together to form protein complexes? How many ribosomes cooperate together? Can we see cooperation between ribosomes that translate different RNA messages? Given the novelty of these fundamental questions in this rapidly expanding field, you will have a unique chance to address them first.<\/p>\n<p><strong>Approach -<\/strong> You will directly follow the unknown dynamics of ribosome translation, protein folding and assembly, and chaperone guidance. This is enabled using optical tweezers combined with single-molecule fluorescence, which detect changes in individual molecules at nanometer and millisecond resolution. In collaboration with our partners, you will also use selective ribosome profiling \u2013 an RNA sequencing method that provides high-level data across the genome an <em>in-vivo<\/em>. This first look may reveal a host of unexpected phenomena. You will develop new experimental schemes, Use cutting-edge single-molecule fluorescence and manipulation methods, Adapt existing biochemical protocols, Analyze the complex temporal data, formulation of new models, And explain your findings in high-level scientific papers.<\/p>\n<p><strong>International team -<\/strong> You will be part of a collaboration with leading groups at Heidelberg University and the ETH in Zurich, which use novel sequencing and cryo-EM methods. By working within this motivated group of young scientists, you will obtain a unique training, understanding and skill set in this expanding field. By integrating these approaches, you will provide insights of unprecedented detail, spanning from the cellular to the atomic level, from <em>in vivo<\/em> to <em>in vitro<\/em>, from genome-wide patterns to molecular mechanisms, and from bacteria to human cells.<\/p>\n<p>Image left show ribosome (blue, orange) that synthesized protein chain (yellow) by translating the RNA message (red). Image right shows dynamic ribosome interactions.<\/p>\n<p><strong>Qualifications<\/strong><br \/>We have a number of positions available (PhD and PD). We are looking for outstanding experimental physicists or chemists with an interest in single-molecule techniques, ambition to make breakthrough findings, programming skills to handle complex data, and who thrive in a diverse, collaborative, and supportive environment. Excellent verbal and written English skills are essential.<\/p>\n<p><strong>Work environment<\/strong><br \/>AMOLF is a part of NWO-I and initiate and performs leading fundamental research on the physics of complex forms of matter, and to create new functional materials, in partnership with academia and industry. The institute is located at Amsterdam Science Park and currently employs about 140 researchers and 80 support employees. <a href=\"http:\/\/www.amolf.nl\">www.amolf.nl<\/a><\/p>\n<p><strong>Our group -<\/strong> We form a lively and close-knit research group of about 10 PhD students and postdocs, which work together in small teams on various projects in a highly supportive and social atmosphere that extends to the other research groups at the AMOLF institute, which is housed in a modern building in the east of Amsterdam. The Tans group at the AMOLF institute Amsterdam has been at the forefront of studying chaperone-guided protein folding using optical tweezers. This technique allows one to mechanically manipulate individual proteins, and hence follow the movements and folding steps as they fold. We have shown striking sequences of molecular events that underlie chaperone functions, which are invisible with other methods.<\/p>\n<p><a href=\"https:\/\/www.sandertanslab.nl\/\">https:\/\/www.sandertanslab.nl<\/a><\/p>\n<p><a href=\"https:\/\/amolf.nl\/research-groups\/biophysics\">https:\/\/amolf.nl\/research-groups\/biophysics<\/a><\/p>\n<p><strong>Working conditions<\/strong><\/p>\n<ul>\n<li>The working atmosphere at the institute is largely determined by young, enthusiastic, mostly foreign employees. Communication is informal and runs through short lines of communication.<\/li>\n<li>The position is intended as full-time (40 hours \/ week, 12 months \/ year) appointment in the service of the Netherlands Foundation of Scientific Research Institutes (NWO-I) for the duration of four years<\/li>\n<li>Funding is available to attend regularly international conferences.<\/li>\n<li>AMOLF assists any new foreign researcher with housing and visa applications and compensates their transport costs and furnishing expenses.<\/li>\n<\/ul>\n<p><strong>More information?<\/strong><br \/>https:\/\/www.sandertanslab.nl<\/p>\n<p><strong>Application<\/strong><br \/>You can respond to this vacancy online via the button below.<\/p>\n<p>Please annex your:<\/p>\n<ul>\n<li>Resume;<\/li>\n<li>Motivation on why you want to join the group (max. 1 page).<\/li>\n<\/ul>\n<p>It is important to us to know why you want to join our team. Hence, we will only consider your application if it contains your motivation letter.<\/p>\n<p>Applications will be evaluated on a rolling basis and as soon as an excellent match is made, the position will be filled.<\/p>\n<p><em>Online screening may be part of the selection.<\/em><\/p>\n<p><strong>Diversity code<\/strong><br \/>AMOLF is highly committed to an inclusive and diverse work environment: we want to develop talent and creativity by bringing together people from different backgrounds and cultures. We recruit and select on the basis of competencies and talents. We strongly encourage anyone with the right qualifications to apply for the vacancy, regardless of age, gender, origin, sexual orientation or physical ability.<\/p>\n<p>AMOLF has won the NNV Diversity Award 2022, which is awarded every two years by the Netherlands Physical Society for demonstrating the most successful implementation of equality, diversity and inclusion (EDI).<\/p>\n<p><em><strong>Commercial activities in response to this ad are not appreciated.<\/strong><\/em><\/p>\n<p>\n<\/div><\/section><\/div>\n  \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_one_third-0aa7055fe62c3622faec82866afbaeb2\">\n.flex_column.av-av_one_third-0aa7055fe62c3622faec82866afbaeb2{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-av_one_third-0aa7055fe62c3622faec82866afbaeb2 av_one_third flex_column_div av-zero-column-padding  '     ><div  class='togglecontainer av-av_toggle_container-d03efdf7de8d15029af4a4ccb5448be7' ><div class='taglist'><div class=\"tag-tab\"><a href=\"#\" data-tag=\"{All}\" class=\"activeFilter\">All<\/a><span class='tag-seperator'>\/<\/span><\/div><div class=\"tag-tab\"><a href=\"#\" data-tag=\"{Applications}\" class=\"\">Applications<\/a><span class='tag-seperator'>\/<\/span><\/div><div class=\"tag-tab\"><a href=\"#\" data-tag=\"{Views}\" class=\"\">Views<\/a><span class='tag-seperator'>\/<\/span><\/div><\/div>\n              <section class='av_toggle_section av-av_toggle-c97acb92fabb1e65090e2ef688c101dd'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{All} {Applications} {Views} \"  ><p id='toggle-toggle-id-4' data-fake-id='#toggle-id-4' class='toggler  activeTitle av-title-above '  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-4' data-slide-speed=\"200\" data-title=\"Academic Positions\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: Academic Positions\" data-aria_expanded=\"Click to collapse: Academic Positions\">Academic Positions<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/p><div id='toggle-id-4' aria-labelledby='toggle-toggle-id-4' role='region' class='toggle_wrap  active_tc av-title-above' style='display:block;' ><div class='toggle_content invers-color '  itemprop=\"text\" ><p>          \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_font_icon-68df07e82f9aa7e9ca8086cf07328158\">\n.av_font_icon.av-av_font_icon-68df07e82f9aa7e9ca8086cf07328158 .av-icon-char{\nfont-size:12px;\nline-height:12px;\n}\n<\/style>\n<span  class='av_font_icon av-av_font_icon-68df07e82f9aa7e9ca8086cf07328158 avia_animate_when_visible av-icon-style- avia-icon-pos-left avia-iconfont avia-font-entypo-fontello av-no-color avia-icon-animate'><span class='av-icon-char' data-av_icon='\ue82d' data-av_iconfont='entypo-fontello' aria-hidden=\"true\" ><\/span><\/span> 15 applications<br \/>\n          \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_font_icon-2ad3e02231965e18a13969aa2ae9da8b\">\n.av_font_icon.av-av_font_icon-2ad3e02231965e18a13969aa2ae9da8b .av-icon-char{\nfont-size:12px;\nline-height:12px;\n}\n<\/style>\n<span  class='av_font_icon av-av_font_icon-2ad3e02231965e18a13969aa2ae9da8b avia_animate_when_visible av-icon-style- avia-icon-pos-left avia-iconfont avia-font-entypo-fontello av-no-color avia-icon-animate'><span class='av-icon-char' data-av_icon='\ue80b' data-av_iconfont='entypo-fontello' aria-hidden=\"true\" ><\/span><\/span> 180 views                  <\/p>\n<\/div><\/div><\/div><\/section>\n          <\/div><\/div>\n  <br style=\"clear: both\">\n  <span style=\"margin-top: 20px; float: right\">25-04-2026<\/span>\n  <span style=\"margin-top: 20px; font-weight: bold; float: left\">AMOLF<\/span>\n  <hr>  \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_two_third-61be9178410eaaa3f443d4723cbbaeb0\">\n.flex_column.av-av_two_third-61be9178410eaaa3f443d4723cbbaeb0{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-av_two_third-61be9178410eaaa3f443d4723cbbaeb0 av_two_third first flex_column_div av-zero-column-padding  '     ><section  class='av_textblock_section av-av_textblock-0366cc7376be6c9e82a3e9cc8987b64f '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><h5 class=\"no-translation\">Postdoc: Inverse design of broadband multi-parameter nanophotonic sensors<\/h5>\n<p class=\"no-translation\"><strong>Work Activities<\/strong><br \/>The <em>Photonic Forces <\/em>group at AMOLF is looking for a motivated and talented postdoctoral researcher to join an ambitious interdisciplinary project on next-generation optical sensing technologies. In this project, you will develop novel theoretical and numerical methods for the inverse design of nanophotonic structures enabling broadband, multiparameter sensing in fiber-based systems.<\/p>\n<p>The project is a collaboration between AMOLF, TU Eindhoven, and industrial partners, aiming to establish a new paradigm for nanophotonic fiber sensing. Modern industry increasingly relies on real-time monitoring of various quantities, such as pressure, temperature, and acceleration. While optical sensors have great advantages, they are challenged by high cost and the difficulty to distinguish various physical quantities. We address these challenges by developing broadband nanophotonic sensors that disentangle multiple physical parameters from complex optical spectra. This approach raises fundamental questions on how information about parameters is optimally encoded and retrieved from light. In particular, it requires understanding how multimode photonic systems respond to mechanical and thermal perturbations, what sets the ultimate precision limits of such measurements, and how nanophotonic structures can be designed to approach these limits.<\/p>\n<p>As a postdoc, you will develop theoretical models and inverse design strategies for optomechanical nanophotonic transducers. You will investigate how to engineer their spectral response for multiparameter sensing, guided by fundamental bounds on estimation precision, and implement advanced computational design methods to realize optimal structures. Your work will directly connect fundamental concepts in nanophotonics and measurement theory to the development of new sensing technologies, in close collaboration with experimental researchers and industrial partners.<\/p>\n<p>Our group offers an open and collaborative environment in which we focus on hands-on learning and personal growth of all group members. We are looking for excited and talented candidates, who are eager to develop new skills and engage new challenges in close collaboration with colleagues.<\/p>\n<p><strong>Please send your application at the latest by May 28, 2026.<\/strong><\/p>\n<p><strong>Qualifications<\/strong><br \/>We seek an excellent candidate with a background in physics or engineering, with relevant experience in nanophotonic theory and\/or novel automated design approaches. You need to have a doctoral degree, or have met all the requirements and will receive the doctoral degree shortly. The successful candidate has a collaborative spirit, and will liaise with collaborators. We strongly believe in the benefits of an inclusive and diverse workplace, and encourage people from all backgrounds to apply.<\/p>\n<p><strong>Work environment<\/strong><br \/>The <em>Photonic Forces<\/em> team led by prof. Ewold Verhagen studies light-matter interactions at the nanoscale, in devices ranging from photonic crystals and metamaterials to high-quality optical resonators. We investigate the fundamental physics associated with such interactions, which are enhanced through optical field confinement in tailored nanophotonic systems, as well as the applications they allow. In particular, we study new ways to measure and control both light and motion down to the fundamental limits governed by physical laws and symmetries. Theory and experiment go hand in hand in many projects in the group. Within the group as well as among the different groups at AMOLF, we have a strong focus on stimulating development of junior researchers in all professional aspects, as well as collaborations with other researchers at AMOLF and beyond. We strive to create a diverse and inclusive environment where passion and enjoyment of science can shine. For more information, see <a href=\"http:\/\/www.optomechanics.nl\">www.optomechanics.nl<\/a>.<\/p>\n<p>AMOLF is a part of NWO-I and initiate and performs leading fundamental research on the physics of complex forms of matter, and to create new functional materials, in partnership with academia and industry. The institute is located at Amsterdam Science Park and currently employs about 140 researchers and 80 support employees. <a href=\"http:\/\/www.amolf.nl\">www.amolf.nl<\/a><\/p>\n<p><strong>Working conditions<\/strong><\/p>\n<ul>\n<li>The working atmosphere at AMOLF is largely determined by young, enthusiastic, mostly foreign employees. Communication is informal and runs through short lines of communication.<\/li>\n<li>The position is intended as full-time (40 hours \/ week, 12 months \/ year) appointment in the service of the Netherlands Foundation of Scientific Research Institutes (NWO-I) for the duration of 1.5 years<\/li>\n<li>Salary is in scale 10 (<a href=\"http:\/\/www.nwo-i.nl\/en\/employees\/employment-regulations\">CAO-OI<\/a>) which starts at 4.552 Euro\u2019s gross per month, and a <a href=\"https:\/\/www.nwo-i.nl\/en\/working-at-nwo-i\/informationforapplicants\/\">range of employment benefits<\/a>.<\/li>\n<li>AMOLF assists any new foreign Postdoc with housing and visa applications and compensates their transport costs and furnishing expenses.<\/li>\n<\/ul>\n<p><strong>More information?<\/strong><br \/>For further information about the position, please contact Ewold Verhagen: verhagen@amolf.nl.<\/p>\n<p><strong>Application<\/strong><br \/>You can respond to this vacancy online via the button below, at the latest by May 28, 2026.<\/p>\n<p><em>Online screening may be part of the selection.<\/em><\/p>\n<p><strong>Diversity code<\/strong><br \/>AMOLF is highly committed to an inclusive and diverse work environment: we want to develop talent and creativity by bringing together people from different backgrounds and cultures. We recruit and select on the basis of competencies and talents. We strongly encourage anyone with the right qualifications to apply for the vacancy, regardless of age, gender, origin, sexual orientation or physical ability.<\/p>\n<p>AMOLF has won the NNV Diversity Award 2022, which is awarded every two years by the Netherlands Physical Society for demonstrating the most successful implementation of equality, diversity and inclusion (EDI).<\/p>\n<p><em><strong>Commercial activities in response to this ad are not appreciated.<\/strong><\/em><\/p>\n<p>\n<\/div><\/section><\/div>\n  \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_one_third-0aa7055fe62c3622faec82866afbaeb2\">\n.flex_column.av-av_one_third-0aa7055fe62c3622faec82866afbaeb2{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-av_one_third-0aa7055fe62c3622faec82866afbaeb2 av_one_third flex_column_div av-zero-column-padding  '     ><div  class='togglecontainer av-av_toggle_container-d03efdf7de8d15029af4a4ccb5448be7' ><div class='taglist'><div class=\"tag-tab\"><a href=\"#\" data-tag=\"{All}\" class=\"activeFilter\">All<\/a><span class='tag-seperator'>\/<\/span><\/div><div class=\"tag-tab\"><a href=\"#\" data-tag=\"{Applications}\" class=\"\">Applications<\/a><span class='tag-seperator'>\/<\/span><\/div><div class=\"tag-tab\"><a href=\"#\" data-tag=\"{Views}\" class=\"\">Views<\/a><span class='tag-seperator'>\/<\/span><\/div><\/div>\n              <section class='av_toggle_section av-av_toggle-c97acb92fabb1e65090e2ef688c101dd'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div role=\"tablist\" class=\"single_toggle\" data-tags=\"{All} {Applications} {Views} \"  ><p id='toggle-toggle-id-5' data-fake-id='#toggle-id-5' class='toggler  activeTitle av-title-above '  itemprop=\"headline\"  role='tab' tabindex='0' aria-controls='toggle-id-5' data-slide-speed=\"200\" data-title=\"Academic Positions\" data-title-open=\"\" data-aria_collapsed=\"Click to expand: Academic Positions\" data-aria_expanded=\"Click to collapse: Academic Positions\">Academic Positions<span class=\"toggle_icon\"><span class=\"vert_icon\"><\/span><span class=\"hor_icon\"><\/span><\/span><\/p><div id='toggle-id-5' aria-labelledby='toggle-toggle-id-5' role='region' class='toggle_wrap  active_tc av-title-above' style='display:block;' ><div class='toggle_content invers-color '  itemprop=\"text\" ><p>          \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_font_icon-68df07e82f9aa7e9ca8086cf07328158\">\n.av_font_icon.av-av_font_icon-68df07e82f9aa7e9ca8086cf07328158 .av-icon-char{\nfont-size:12px;\nline-height:12px;\n}\n<\/style>\n<span  class='av_font_icon av-av_font_icon-68df07e82f9aa7e9ca8086cf07328158 avia_animate_when_visible av-icon-style- avia-icon-pos-left avia-iconfont avia-font-entypo-fontello av-no-color avia-icon-animate'><span class='av-icon-char' data-av_icon='\ue82d' data-av_iconfont='entypo-fontello' aria-hidden=\"true\" ><\/span><\/span> 93 applications<br \/>\n          \n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_font_icon-2ad3e02231965e18a13969aa2ae9da8b\">\n.av_font_icon.av-av_font_icon-2ad3e02231965e18a13969aa2ae9da8b .av-icon-char{\nfont-size:12px;\nline-height:12px;\n}\n<\/style>\n<span  class='av_font_icon av-av_font_icon-2ad3e02231965e18a13969aa2ae9da8b avia_animate_when_visible av-icon-style- avia-icon-pos-left avia-iconfont avia-font-entypo-fontello av-no-color avia-icon-animate'><span class='av-icon-char' data-av_icon='\ue80b' data-av_iconfont='entypo-fontello' aria-hidden=\"true\" ><\/span><\/span> 260 views                  <\/p>\n<\/div><\/div><\/div><\/section>\n          <\/div><\/div>\n  <br style=\"clear: both\">\n  <span style=\"margin-top: 20px; float: right\">10-04-2026<\/span>\n  <span style=\"margin-top: 20px; font-weight: bold; float: left\">AMOLF<\/span>\n  \n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":7671,"comment_status":"open","ping_status":"closed","template":"","meta":{"footnotes":""},"tags":[],"portfolio_entries":[180,148],"class_list":["post-7675","portfolio","type-portfolio","status-publish","has-post-thumbnail","hentry","portfolio_entries-scientific-research-institutes","portfolio_entries-ubeeo-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - 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