PhD candidates 'Improving Treatment of Chronic Subdural Hematoma'

Job description
We invite applications for two PhD positions within a large international research consortium dedicated to minimally invasive neurosurgical procedures. The project focuses on chronic subdural hematoma (cSDH), a highly prevalent condition in an aging population and one of the most frequently treated neurosurgical disorders.

The overall goal of this project is to optimize the safety and effectiveness of cSDH treatment through high-quality clinical research. The project consists of several complementary studies, including an international multicenter randomized clinical trial and a nationwide prospective registry.

Together, these studies will generate robust evidence to guide future clinical practice. To strengthen our research team, we are recruiting two PhD candidates who will each focus on a key component of the project while working closely together within a shared research program.

Each PhD Candidate will have a distinct primary focus:

• PhD Candidate one – clinical trial: Focus on the preparation, conduct, and analysis of an international multicenter randomized trial.
• PhD Candidate two – registry: Focus on the setup, coordination, and analysis of a nationwide chronic subdural hematoma registry.

Both candidates will contribute to protocol development, data analysis, and scientific dissemination, and will collaborate closely with each other, the postdoctoral researcher, and the principal investigators. In addition to the trial and registry, the project also includes essential methodological work on the development of a surgical simulator training module and patient‑reported outcome measures (PROMs).

These components are integral to the project and will be distributed between the two PhD candidates based on interest and expertise during the course of the PhD trajectories. The positions are offered for a duration of 4 years, culminating in a PhD thesis based on multiple peer-reviewed publications.

Key Responsibilities

• Contribute to the scientific design and execution of studies within the cSDH project.
• Collect, manage, and analyze clinical data.
• Perform statistical analyses under supervision and in collaboration with biostatisticians.
• Prepare manuscripts for peer-reviewed journals and contribute to conference presentations.
• Participate actively in team meetings and international collaborations.
• Actively contribute to a collaborative, transparent, and safe research environment.

Position-Specific Activities

Clinical Trial PhD Candidate

• Support the coordination and execution of an international multicenter trial.
• Assist with ethics approvals, regulatory documentation, and trial monitoring.
• Maintain close contact with participating centers to ensure protocol adherence and data quality.
• Perform trial-related statistical analyses and contribute to reporting of results.

Registry PhD Candidate

• Coordinate data collection with hospitals participating in the national registry.
• Support registry governance, data quality control, and database development.
• Conduct observational studies and outcome analyses using registry data.
• Contribute to registry-based methodological and clinical publications.

What we offer:

• A 4-year PhD appointment within a high-impact clinical research program.
• Supervision by an experienced, multidisciplinary research team.
• Training in clinical research methods, statistics, and scientific writing.
• Opportunities to collaborate (inter)nationally and build a strong academic network.
• Opportunities to (co-)author high-quality publications in leading journals in neurosurgery, neurotrauma, and clinical research.
• Opportunities to present work at major scientific meetings.
• A stimulating research environment with attention to well-being and professional development.

Adviseur calamiteiten- en crisismanagement

Functie
Als adviseur calamiteiten- en crisismanagement zorg je ervoor dat het Radboudumc aantoonbaar voorbereid is op calamiteiten en crisissituaties. Jij houdt het overzicht, brengt beleid en praktijk samen en helpt collega’s binnen het ziekenhuis om in onverwachte situaties doelmatig en effectief te handelen.

In deze rol werk je samen met collega’s van Beveiliging en Ontvangst, het Servicebedrijf, managers van organisatie-eenheden in zorg, onderzoek en onderwijs en functionarissen binnen de crisisorganisatie. Ook stem je af met externe partners in de regio, zoals collega ziekenhuizen, de Acute Zorgregio en de Veiligheidsregio en veiligheidsorganisaties.

Wat deze functie aantrekkelijk maakt? Je hebt veel inhoudelijke invloed, werkt ziekenhuisbreed en draagt door jouw goede organisatie indirect bij aan de veiligheid van patiënten, bezoekers en collega’s. Je stelt scherp prioriteiten en schakelt bewust tussen je rollen als adviseur, organisator, opdrachtgever, plannenmaker en functioneel leidinggevende van de calamiteitencoördinatoren.

Je belangrijkste taken en verantwoordelijkheden zijn:

• Beheren, actualiseren en verder ontwikkelen van het crisis- en calamiteitenplan van het Radboudumc.
• Adviseren van managers en functionarissen over calamiteiten- en crisismanagement, zowel inhoudelijk als procesmatig.
• Vertalen van interne en externe ontwikkelingen, audits en evaluaties naar verbeteringen in beleid en procedures.
• Regisseren en (laten) organiseren van het Opleidings-, Trainings- en Oefenprogramma voor de crisisorganisatie.
• Coördineren en coachen van de calamiteitencoördinatoren en hun kennisoverleg.
• Organiseren en begeleiden van (grootschalige) oefeningen, zoals de ziekenhuisrampenoefening.
• Vertegenwoordigen van het Radboudumc in relevante regionale en landelijke overleggen.

Bedrijfsvoerder afdeling Apotheek, Farmacologie en Toxicologie

Functie
Heb jij een scherp analytisch vermogen én een talent voor het inzichtelijk maken, beheren en optimaliseren van processen in bedrijfsvoering? Wil je werken in een dynamische omgeving en bijdragen aan het verbeteren van zorg, onderzoek en onderwijs door slimme bedrijfsvoering? Dan is deze functie als bedrijfsvoerder iets voor jou!

Als bedrijfsvoerder ben jij de verbindende schakel tussen strategie en uitvoering. Je helpt leidinggevenden grip te krijgen op hun bedrijfsvoering en ondersteunt hen met scherpe analyses, heldere adviezen en concrete verbeteringen.

Je werkt vanuit het Bedrijfsbureau, maar staat midden in de organisatie: je schakelt intensief met verschillende secties en stakeholders. Bovendien krijg je de ruimte om mee te bouwen aan de verdere ontwikkeling van het Bedrijfsbureau zelf.

Je rapporteert aan de Manager Bedrijfsbureau.

Wat ga je doen?
Adviseren met impact

• Je adviseert het tactisch management over capaciteit, financiën en personeelsinzet.
• Je levert input voor strategische keuzes en helpt organisatiedoelen te realiseren.
• Je vertaalt interne en externe ontwikkelingen naar concreet beleid.
• Je bent een stevige gesprekspartner in overleggen binnen en buiten de afdeling.

Realiseren en verbeteren

• Je ontwikkelt en implementeert slimme werkwijzen en processen.
• Je coördineert projecten gericht op procesoptimalisatie en efficiëntie.
• Je ondersteunt leidinggevenden bij het creëren van een resultaatgerichte werkomgeving.
• Je beheert contracten, SLA’s en financiële afspraken en bewaakt budgetten.

Sturen op data

• Je verzamelt, analyseert en vertaalt data naar bruikbare inzichten.
• Je maakt heldere managementrapportages en adviseert over bijsturing.
• Je draagt actief bij aan de planning & controlcyclus.
• Je signaleert kansen en knelpunten en zet deze om in concrete verbeteracties.

Postdoc Computational Biology and Omics

Job description
Retinal diseases such as age-related macular degeneration (AMD), diabetic retinopathy, and inherited retinal disorders are leading causes of blindness worldwide. Traditional models (animal or 2D cell cultures) fail to fully replicate the complex structure, vascularization, and function of the human retina. Retinal organoids-on-chip offer a breakthrough: they recreate 3D retinal architecture, allow integration of microvasculature, and enable real-time functional studies through electrophysiology. This platform provides an unprecedented window into human retinal disease mechanisms, and potential therapeutic interventions.

We invite applications for a postdoctoral researcher to join our interdisciplinary team at the interface of computational biology, multi-omics data analysis, and systems biology. Our group specializes in integrating high-dimensional omics data with functional electrophysiology from patient-derived stem cell models, enabling unique insights into disease mechanisms and cellular function.

Position Overview:
We are seeking a highly motivated researcher with expertise in computational analysis of multi-omics datasets (e.g., genomics, transcriptomics, proteomics, metabolomics) and a strong interest in integrative systems biology approaches. The successful candidate will work on cutting-edge projects that combine multi-omics datasets with electrophysiology measurements from patient-derived stem cell models to explore disease mechanisms, cellular regulatory networks, and functional phenotypes. This is an exciting opportunity to work in a team that bridges computational analysis with translational experimental validation.

This research will focus on addressing these critical challenges, helping to pioneer innovative solutions for vision preservation and restoration.

Policy Advisor Radboudumc Global Health

Job description
As policy officer global health, you support the further development and day-to-day functioning of Radboudumc Global Health (RGH) in close collaboration with the RGH coordination group.

You help translate shared priorities into concrete actions, connect colleagues and initiatives across Radboudumc, strengthen collaboration with Radboud University, and support the development and coordination of strategic partnerships in the Netherlands and internationally.

In this role, you will play a central part in strengthening and further professionalizing Global Health within Radboudumc. It is a dynamic position at the intersection of strategy, collaboration, and implementation, where you actively contribute to shaping and advancing our global health ambitions. You will work closely with the RGH coordination group and engage with a broad network of internal and external partners

Your responsibilities:

• Support the RGH coordination group in translating strategic priorities into concrete actions and deliverables.
• Connect and activate the internal Global Health network within Radboudumc.
• Support collaboration with Radboud University and relevant cross-institutional initiatives.
• Coordinate activities with national and international partners and contribute to the development of strategic partnerships.
• Organize and facilitate meetings, while ensuring follow-up and progress.
• Monitor progress on agreed priorities and address delays or lack of clarity in responsibilities.
• Contribute to the internal communication, visibility, and organizational coherence of RGH.