PhD Position Additively manufactured biodegradable bone substitutes with tunable degradation

Job description
Faculty of Mechanical Engineering, TU Delft — Departments of Precision and Microsystems Engineering (PME) & Biomechanical Engineering (BME)

Are you excited by the idea of engineering next-generation regenerative implants? Do you want to combine additive manufacturing, materials science, biomechanics, and physics- and machine learning-based modeling to create transformative medical solutions? Join us in this ambitious collaboration between the PME and BME departments, and help shape the future of patient-specific bone replacement.

In this PhD project, you will develop biodegradable porous bone substitutes produced through additive manufacturing of metal-ceramic composites. These architected implants will be tailored for mechanical performance and controlled degradation, enabling safe and effective regeneration in load-bearing environments.

Your core challenge is to understand and predict how geometry, material composition, and manufacturing parameters drive quasi-static performance, biodegradation kinetics, and manufacturability. You will employ a combined physics-based and machine-learning modelling approach, supported by in-vitro mechanical and degradation experiments for validation.

The developed porous structures will integrate seamlessly with macro-geometries and topologically optimized architectures from sibling PhD projects, delivering a fully engineered, patient-specific bone-replacement solution.

This PhD position is part of a Marie Skłodowska-Curie Doctoral Network (Horizon Europe). As an MSCA Doctoral Candidate, you will join a vibrant international cohort, participate in network-wide schools and workshops, and pursue mandatory research secondments abroad. The MSCA framework offers exceptional training, mobility, and career-development opportunities

Job requirements
Your Key Responsibilities:

• Investigate the role of design parameters, architecture, material composition, and AM process settings on mechanical performance and degradation behavior.
• Develop physics-based and data-driven models to link geometry, materials, and biodegradation kinetics.
• Conduct in-vitro mechanical tests and biodegradation experiments to validate models.
• Collaborate closely with researchers at PME and BME, as well as with the wider MSCA network.
• Interface your designs with macro-scale implant geometries and topology-optimized structures from sibling projects.

Your Profile

We are looking for a highly motivated candidate with:

• Master’s degree in Mechanical Engineering, Materials Science, Biomedical Engineering, Applied Physics, or a related field.
• Knowledge of additive manufacturing, biomaterials, or mechanical testing.
• Strong background in lab works including material characterization, chemical process, and in vitro testing.
• Experience with programming (e.g., Python, Julia) is a plus.
• Interest in biomechanics, biodegradable materials, and design for AM.
• Good communication skills and the ability to work in a multidisciplinary team.
• Willingness to relocate and undertake international secondments.
• Compliance with MSCA mobility rule: you must not have lived or carried out your main activity (work, studies) in the Netherlands for more than 12 months in the past 36 months.

What we offer:

• A fully funded PhD position within a prestigious MSCA Doctoral Network.
• Close supervision and mentorship from both PME and BME departments at TU Delft.
• Access to state-of-the-art additive manufacturing and experimental characterization facilities.
• Training through network-wide workshops, summer schools, and transferable-skills programmes.
• Research secondments with international academic and industrial partners.
• Collaboration with a cohort of Doctoral Candidates working toward an integrated, patient-specific implant design pipeline.

TU Delft (Delft University of Technology)
Delft University of Technology is built on strong foundations. As creators of the world-famous Dutch waterworks and pioneers in biotech, TU Delft is a top international university combining science, engineering and design. It delivers world class results in education, research and innovation to address challenges in the areas of energy, climate, mobility, health and digital society. For generations, our engineers have proven to be entrepreneurial problem-solvers, both in business and in a social context.

At TU Delft we embrace diversity as one of our core values and we actively engage to be a university where you feel at home and can flourish. We value different perspectives and qualities. We believe this makes our work more innovative, the TU Delft community more vibrant and the world more just. Together, we imagine, invent and create solutions using technology to have a positive impact on a global scale. That is why we invite you to apply. Your application will receive fair consideration.

Challenge. Change. Impact!

Faculty Mechanical Engineering
From chip to ship. From machine to human being. From idea to solution. Driven by a deep-rooted desire to understand our environment and discover its underlying mechanisms, research and education at the ME faculty focusses on fundamental understanding, design, production including application and product improvement, materials, processes and (mechanical) systems.

ME is a dynamic and innovative faculty with high-tech lab facilities and international reach. It’s a large faculty but also versatile, so we can often make unique connections by combining different disciplines. This is reflected in ME’s outstanding, state-of-the-art education, which trains students to become responsible and socially engaged engineers and scientists. We translate our knowledge and insights into solutions to societal issues, contributing to a sustainable society and to the development of prosperity and well-being. That is what unites us in pioneering research, inspiring education and (inter)national cooperation.

Click here to go to the website of the Faculty of Mechanical Engineering. Do you want to experience working at our faculty? These videos will introduce you to some of our researchers and their work.

PhD Position Additively manufactured biodegradable bone substitutes with tunable degradation

Job description
Faculty of Mechanical Engineering, TU Delft — Departments of Precision and Microsystems Engineering (PME) & Biomechanical Engineering (BME)

Are you excited by the idea of engineering next-generation regenerative implants? Do you want to combine additive manufacturing, materials science, biomechanics, and physics- and machine learning-based modeling to create transformative medical solutions? Join us in this ambitious collaboration between the PME and BME departments, and help shape the future of patient-specific bone replacement.

In this PhD project, you will develop biodegradable porous bone substitutes produced through additive manufacturing of metal-ceramic composites. These architected implants will be tailored for mechanical performance and controlled degradation, enabling safe and effective regeneration in load-bearing environments.

Your core challenge is to understand and predict how geometry, material composition, and manufacturing parameters drive quasi-static performance, biodegradation kinetics, and manufacturability. You will employ a combined physics-based and machine-learning modelling approach, supported by in-vitro mechanical and degradation experiments for validation.

The developed porous structures will integrate seamlessly with macro-geometries and topologically optimized architectures from sibling PhD projects, delivering a fully engineered, patient-specific bone-replacement solution.

This PhD position is part of a Marie Skłodowska-Curie Doctoral Network (Horizon Europe). As an MSCA Doctoral Candidate, you will join a vibrant international cohort, participate in network-wide schools and workshops, and pursue mandatory research secondments abroad. The MSCA framework offers exceptional training, mobility, and career-development opportunities

Job requirements
Your Key Responsibilities:

• Investigate the role of design parameters, architecture, material composition, and AM process settings on mechanical performance and degradation behavior.
• Develop physics-based and data-driven models to link geometry, materials, and biodegradation kinetics.
• Conduct in-vitro mechanical tests and biodegradation experiments to validate models.
• Collaborate closely with researchers at PME and BME, as well as with the wider MSCA network.
• Interface your designs with macro-scale implant geometries and topology-optimized structures from sibling projects.

Your Profile

We are looking for a highly motivated candidate with:

• Master’s degree in Mechanical Engineering, Materials Science, Biomedical Engineering, Applied Physics, or a related field.
• Knowledge of additive manufacturing, biomaterials, or mechanical testing.
• Strong background in lab works including material characterization, chemical process, and in vitro testing.
• Experience with programming (e.g., Python, Julia) is a plus.
• Interest in biomechanics, biodegradable materials, and design for AM.
• Good communication skills and the ability to work in a multidisciplinary team.
• Willingness to relocate and undertake international secondments.
• Compliance with MSCA mobility rule: you must not have lived or carried out your main activity (work, studies) in the Netherlands for more than 12 months in the past 36 months.

What we offer:

• A fully funded PhD position within a prestigious MSCA Doctoral Network.
• Close supervision and mentorship from both PME and BME departments at TU Delft.
• Access to state-of-the-art additive manufacturing and experimental characterization facilities.
• Training through network-wide workshops, summer schools, and transferable-skills programmes.
• Research secondments with international academic and industrial partners.
• Collaboration with a cohort of Doctoral Candidates working toward an integrated, patient-specific implant design pipeline.

TU Delft (Delft University of Technology)
Delft University of Technology is built on strong foundations. As creators of the world-famous Dutch waterworks and pioneers in biotech, TU Delft is a top international university combining science, engineering and design. It delivers world class results in education, research and innovation to address challenges in the areas of energy, climate, mobility, health and digital society. For generations, our engineers have proven to be entrepreneurial problem-solvers, both in business and in a social context.

At TU Delft we embrace diversity as one of our core values and we actively engage to be a university where you feel at home and can flourish. We value different perspectives and qualities. We believe this makes our work more innovative, the TU Delft community more vibrant and the world more just. Together, we imagine, invent and create solutions using technology to have a positive impact on a global scale. That is why we invite you to apply. Your application will receive fair consideration.

Challenge. Change. Impact!

Faculty Mechanical Engineering
From chip to ship. From machine to human being. From idea to solution. Driven by a deep-rooted desire to understand our environment and discover its underlying mechanisms, research and education at the ME faculty focusses on fundamental understanding, design, production including application and product improvement, materials, processes and (mechanical) systems.

ME is a dynamic and innovative faculty with high-tech lab facilities and international reach. It’s a large faculty but also versatile, so we can often make unique connections by combining different disciplines. This is reflected in ME’s outstanding, state-of-the-art education, which trains students to become responsible and socially engaged engineers and scientists. We translate our knowledge and insights into solutions to societal issues, contributing to a sustainable society and to the development of prosperity and well-being. That is what unites us in pioneering research, inspiring education and (inter)national cooperation.

Click here to go to the website of the Faculty of Mechanical Engineering. Do you want to experience working at our faculty? These videos will introduce you to some of our researchers and their work.

Phd Position Development of Digital Twin Based Platform for Simulating Thrombectomy Procedures

Job description
We are looking for an enthusiastic PhD candidate to join a multidisciplinary project on improving minimally invasive stroke treatment using advanced computer simulations.

In this project, you will develop and apply in silico models to better understand how blood clots and medical devices interact during thrombectomy procedures. By combining medical imaging, computational modelling, and data-driven methods, the goal is to create virtual patient populations and simulation tools that can support safer, more effective stroke treatments and accelerate medical device innovation.

You will work in an academic environment at the interface of engineering, medicine, and industry, collaborating closely with industrial partners and clinicians. Your tasks will include developing and implementing numerical models, analysing and validating simulation results, and disseminating your work through publications and conference presentations.

More specifically, you will be responsible for developing an in silico platform generating virtual patient populations with comprehensive vessel and thrombus characteristics in collaboration with our industrial partner InSteps. In parallel, you will create a computational device evaluation platform featuring efficient models of stent retrievers and aspiration devices, leveraging Delft's expertise and the simulation capabilities of our second industrial partner, 4RealSim. Finally, you will Integrate these platforms into a unified simulation environment for in silico clinical trials, enabling evaluation of thrombectomy procedures across diverse virtual patient cohorts with various devices and techniques in collaboration with our clinical partners from the Erasmus Medical Center.

The project described above is sponsored in the context of a public-private partnership, which implies that there will be a strong collaboration with our industrial partners and an emphasis on real world application of the tools described above.

You will be based in the CardioVascular Biomechanics Section (https://www.tudelft.nl/me/over/afdelingen/biomechanical-engineering/research/cardiovascular-biomechanics), a research group within the BioMechanical Engineering Department, under the supervision of Prof. Frank Gijsen and Dr. Behrooz Fereidoonnezhad.

Job requirements
Your Profile:

• Strong interest and/or experience in patient-specific computational modelling.
• Have a strong affinity with scientific programming.
• Have experience with Finite Element analysis.
• MSc degree (completed or near completion) from a technical program such as (bio)mechanical engineering or similar fields.
• Be proactive, collaborative mindset and good communication skills in English.

Please highlight your specific skills for this position explicitly in your motivation letter. Motivation letters that do not address any of these requirements will not be considered.

If you are passionate about advancing the field of in silico medicine and digital twin technology and contributing to the future of personalized treatment strategies, we encourage you to apply. Please submit your application, including a CV and cover letter, via the provided application portal.

TU Delft (Delft University of Technology)
Delft University of Technology is built on strong foundations. As creators of the world-famous Dutch waterworks and pioneers in biotech, TU Delft is a top international university combining science, engineering and design. It delivers world class results in education, research and innovation to address challenges in the areas of energy, climate, mobility, health and digital society. For generations, our engineers have proven to be entrepreneurial problem-solvers, both in business and in a social context.

At TU Delft we embrace diversity as one of our core values and we actively engage to be a university where you feel at home and can flourish. We value different perspectives and qualities. We believe this makes our work more innovative, the TU Delft community more vibrant and the world more just. Together, we imagine, invent and create solutions using technology to have a positive impact on a global scale. That is why we invite you to apply. Your application will receive fair consideration.

Challenge. Change. Impact!

Faculty Mechanical Engineering
From chip to ship. From machine to human being. From idea to solution. Driven by a deep-rooted desire to understand our environment and discover its underlying mechanisms, research and education at the ME faculty focusses on fundamental understanding, design, production including application and product improvement, materials, processes and (mechanical) systems.

ME is a dynamic and innovative faculty with high-tech lab facilities and international reach. It’s a large faculty but also versatile, so we can often make unique connections by combining different disciplines. This is reflected in ME’s outstanding, state-of-the-art education, which trains students to become responsible and socially engaged engineers and scientists. We translate our knowledge and insights into solutions to societal issues, contributing to a sustainable society and to the development of prosperity and well-being. That is what unites us in pioneering research, inspiring education and (inter)national cooperation.

Click here to go to the website of the Faculty of Mechanical Engineering. Do you want to experience working at our faculty? These videos will introduce you to some of our researchers and their work.

Postdoc in Digital Twins for Flood-Resilient Infrastructure

Job description

Current and future impact of flooding to critical infrastructure (e.g. dikes, bridges) is a major concern worldwide. Unfortunately, the management of flood-prone structures is extremely challenging because underlying processes are complex and uncertain. If our capacity to anticipate flood-induced impacts on infrastructure does not improve, societal and economic consequences are likely to be unsustainable.

Digital Twins (DTs) offer a promising opportunity to combine recent advances in modelling, data assimilation and machine learning. However, for DTs to support the management of flood-prone infrastructure, they must be effectively integrated with flood-risk modelling. The scientific challenge is to develop methods that enable Digital Twins to leverage multiple models, datasets and computational techniques to improve predictive capacity in real flood-risk contexts.

FlooDT (Digital Twin for flood-resilient infrastructure management) is a prestigious and ambitious project funded by NWO. It aims to develop a new methodological framework to exploit the capability of DTs for managing flood risk “from climate prediction to structure protection”. TU Delft is leading the project and a consortium that involves multiple universities (e.g. ETH Zurich, Univ. Polytechnica of Catalunya) and stakeholders (e.g. Deltares, Rijkswaterstaat). The project has also the support of the TU Delft Digital Competence Centre (DCC).

For this unique project we are seeking a motivated and talented Postdoctoral Researcher for a 3 year appointment. In your role you will:

• Develop a comprehensive catalogue of data and models for flood risk assessment of critical infrastructure.
• Design an integrated workflow for data/models for the interoperability and interaction of such datasets and models.
• Build modular, containerised functionalities that operate consistently across different computing environments.
• Develop the computational back-end of the functional modules by advancing new hybrid physics-based and machine-learning algorithms.
• Organise workshops and coordinate stakeholder engagement (e.g. regular meetings, presentations, visits).

You will join the Flood Risk and Hydraulic Structures section, a collaborative and international team where curiosity, interdisciplinary research and scientific excellence are valued. Our section closely collaborates with the other sections within the Department of Hydraulic Engineering, other departments within our Faculty of Civil Engineering and Geoscience and many research groups around the world. We offer strong support for your professional growth, including mentoring, training, and ample opportunities for international collaboration and networking.

Job requirements
We are looking for an enthusiastic and inquisitive computational researcher who enjoys working in an international and multidisciplinary environment. You have:

• A PhD degree in Computer Science, Hydro-informatics or Civil Engineering (or in a related discipline).
• Demonstrated experience in data management, software development and/or model-data interoperability.
• Scientific and/or practical knowledge of digital twinning or machine learning.
• Excellent programming skills (e.g. in Python, SQL, Java, PyTorch, etc.).
• A critical, creative and pro-active approach to research, with good problem-solving skills.
• Proven experience with writing scientific publications and preparing communications for scientific and technical meetings with project partners.
• Excellent command of English (oral and written).

Previous experience with HPC (High Performance Computing) and ontologies is desirable.

We welcome applications from candidates with diverse backgrounds and perspectives.

TU Delft (Delft University of Technology)
Delft University of Technology is built on strong foundations. As creators of the world-famous Dutch waterworks and pioneers in biotech, TU Delft is a top international university combining science, engineering and design. It delivers world class results in education, research and innovation to address challenges in the areas of energy, climate, mobility, health and digital society. For generations, our engineers have proven to be entrepreneurial problem-solvers, both in business and in a social context.

At TU Delft we embrace diversity as one of our core values and we actively engage to be a university where you feel at home and can flourish. We value different perspectives and qualities. We believe this makes our work more innovative, the TU Delft community more vibrant and the world more just. Together, we imagine, invent and create solutions using technology to have a positive impact on a global scale. That is why we invite you to apply. Your application will receive fair consideration.

Challenge. Change. Impact!

Faculty of Civil Engineering and Geosciences
The Faculty of Civil Engineering & Geosciences (CEG) is committed to outstanding international research and education in the field of civil engineering, applied earth sciences, traffic and transport, water technology, and delta technology. Our research feeds into our educational programmes and covers societal challenges such as climate change, energy transition, resource availability, urbanisation and clean water. Our research projects are conducted in close cooperation with a wide range of research institutions.
CEG is convinced of the importance of open science and supports its scientists in integrating open science in their research practice. The Faculty of CEG comprises 28 research groups in the following seven departments: Materials Mechanics Management & Design, Engineering Structures, Geoscience and Engineering, Geoscience and Remote Sensing, Transport & Planning, Hydraulic Engineering and Water Management.

Click here to go to the website of the Faculty of Civil Engineering & Geosciences.

Phd Position Development of Digital Twin Based Platform for Simulating Thrombectomy Procedures

Job description
We are looking for an enthusiastic PhD candidate to join a multidisciplinary project on improving minimally invasive stroke treatment using advanced computer simulations.

In this project, you will develop and apply in silico models to better understand how blood clots and medical devices interact during thrombectomy procedures. By combining medical imaging, computational modelling, and data-driven methods, the goal is to create virtual patient populations and simulation tools that can support safer, more effective stroke treatments and accelerate medical device innovation.

You will work in an academic environment at the interface of engineering, medicine, and industry, collaborating closely with industrial partners and clinicians. Your tasks will include developing and implementing numerical models, analysing and validating simulation results, and disseminating your work through publications and conference presentations.

More specifically, you will be responsible for developing an in silico platform generating virtual patient populations with comprehensive vessel and thrombus characteristics in collaboration with our industrial partner InSteps. In parallel, you will create a computational device evaluation platform featuring efficient models of stent retrievers and aspiration devices, leveraging Delft's expertise and the simulation capabilities of our second industrial partner, 4RealSim. Finally, you will Integrate these platforms into a unified simulation environment for in silico clinical trials, enabling evaluation of thrombectomy procedures across diverse virtual patient cohorts with various devices and techniques in collaboration with our clinical partners from the Erasmus Medical Center.

The project described above is sponsored in the context of a public-private partnership, which implies that there will be a strong collaboration with our industrial partners and an emphasis on real world application of the tools described above.

You will be based in the CardioVascular Biomechanics Section (https://www.tudelft.nl/me/over/afdelingen/biomechanical-engineering/research/cardiovascular-biomechanics), a research group within the BioMechanical Engineering Department, under the supervision of Prof. Frank Gijsen and Dr. Behrooz Fereidoonnezhad.

Job requirements
Your Profile:

• Strong interest and/or experience in patient-specific computational modelling.
• Have a strong affinity with scientific programming.
• Have experience with Finite Element analysis.
• MSc degree (completed or near completion) from a technical program such as (bio)mechanical engineering or similar fields.
• Be proactive, collaborative mindset and good communication skills in English.

Please highlight your specific skills for this position explicitly in your motivation letter. Motivation letters that do not address any of these requirements will not be considered.

If you are passionate about advancing the field of in silico medicine and digital twin technology and contributing to the future of personalized treatment strategies, we encourage you to apply. Please submit your application, including a CV and cover letter, via the provided application portal.

TU Delft (Delft University of Technology)
Delft University of Technology is built on strong foundations. As creators of the world-famous Dutch waterworks and pioneers in biotech, TU Delft is a top international university combining science, engineering and design. It delivers world class results in education, research and innovation to address challenges in the areas of energy, climate, mobility, health and digital society. For generations, our engineers have proven to be entrepreneurial problem-solvers, both in business and in a social context.

At TU Delft we embrace diversity as one of our core values and we actively engage to be a university where you feel at home and can flourish. We value different perspectives and qualities. We believe this makes our work more innovative, the TU Delft community more vibrant and the world more just. Together, we imagine, invent and create solutions using technology to have a positive impact on a global scale. That is why we invite you to apply. Your application will receive fair consideration.

Challenge. Change. Impact!

Faculty Mechanical Engineering
From chip to ship. From machine to human being. From idea to solution. Driven by a deep-rooted desire to understand our environment and discover its underlying mechanisms, research and education at the ME faculty focusses on fundamental understanding, design, production including application and product improvement, materials, processes and (mechanical) systems.

ME is a dynamic and innovative faculty with high-tech lab facilities and international reach. It’s a large faculty but also versatile, so we can often make unique connections by combining different disciplines. This is reflected in ME’s outstanding, state-of-the-art education, which trains students to become responsible and socially engaged engineers and scientists. We translate our knowledge and insights into solutions to societal issues, contributing to a sustainable society and to the development of prosperity and well-being. That is what unites us in pioneering research, inspiring education and (inter)national cooperation.

Click here to go to the website of the Faculty of Mechanical Engineering. Do you want to experience working at our faculty? These videos will introduce you to some of our researchers and their work.