PhD Position in Single-Molecule Biophysic

Job description

We are looking for a PhD student passionate about understanding molecular mechanisms in biological systems. This position involves applying single-molecule techniques to study molecular interactions, including protein-ligand interactions and protein-peptide interactions. The candidate will work in an interdisciplinary environment, combining experimental approaches (single molecule fluorescence and biochemistry) with computational methods. The candidate will obtain single-molecule multiplexing data and validate machine learning predictions using the high-throughput data. The successful candidate will collaborate with international partners for therapeutic applications of this research. The project offers opportunities to make significant contributions to understanding molecular interactions and their implications for both fundamental and medical sciences.

Job requirements

• MSc degree (or nearing completion) in physics, biophysics, computational biology, or a related field.
• Strong programming skills (Python) and experience in data analysis and computational methods.
• Familiarity with molecular biology techniques.
• Excellent written and spoken English skills.
• Ability to work effectively in a collaborative, international, and interdisciplinary environment.

This position is part of a Marie Skłodowska-Curie Doctoral Network. Applicants must satisfy the MSCA mobility rule: at the time of recruitment, they must not have lived or carried out their main activity, such as work or study, in the Netherlands for more than 12 months during the previous 36 months. The rule applies regardless of nationality.

TU Delft (Delft University of Technology)
Working at TU Delft means contributing to solutions that really make a difference.

For over 180 years, we have been training engineers who make an impact worldwide in companies, government bodies, or as entrepreneurs. Our alumni turn knowledge into concrete solutions for the challenges of today and tomorrow.

These challenges are changing rapidly. That is why we focus on themes such as energy, climate, digitalisation, artificial intelligence (AI), and smart mobility every day. Our education and research are directly aligned with what society needs now and in the future.

At TU Delft, our people make the difference. With their knowledge and curiosity, our staff provide a high-quality education and conduct pioneering research that extends beyond the campus. You will have the opportunity to take the initiative, work with others, and grow as a professional.

Working at TU Delft means join an international community of professionals and students. Together, we create knowledge, innovations, and solutions that help move the world forward.

Faculty Applied Sciences
With more than 1,100 employees, including 150 pioneering principal investigators, as well as a population of about 3,600 passionate students, the Faculty of Applied Sciences is an inspiring scientific ecosystem. Focusing on key enabling technologies, such as quantum- and nanotechnology, photonics, biotechnology, synthetic biology and materials for energy storage and conversion, our faculty aims to provide solutions to important problems of the 21st century. To that end, we educate innovative students in broad Bachelor's and specialist Master's programmes with a strong research component. Our scientists conduct ground-breaking fundamental and applied research in the fields of Life and Health Science & Technology, Nanoscience, Chemical Engineering, Radiation Science & Technology, and Engineering Physics. We are also training the next generation of high school teachers.

Click here to go to the website of the Faculty of Applied Sciences.

Postdoc Understanding and Improving Robustness of Yeast in an Industrial Process

Job description

You will join a vibrant and collaborative research environment within the Industrial Microbiology section of the Department of Biotechnology at TU Delft. The section brings together six principal investigators and a diverse international team of postdoctoral researchers, PhD candidates and technicians with complementary expertise in modelling, molecular biology, genomics, microbial physiology, synthetic biology and metabolic engineering. This multidisciplinary environment provides excellent opportunities for scientific exchange and collaboration.

This project, co-supervised by professors Jack Pronk and Jean-Marc Daran, is conducted in close collaboration with a leading biotechnology company. It focuses on understanding the molecular basis of a key robustness trait in a yeast-based production process that is already deployed at industrial scale. This unique setting offers an excellent opportunity to address fundamental questions in microbial physiology while working on a challenge of direct relevance to industrial biotechnology.

The successful candidate will investigate the cellular and molecular mechanisms underlying robustness in industrial yeast strains and translate this knowledge into rational strategies for strain improvement. The project will combine cell biology, genome editing and quantitative physiological studies in laboratory bioreactors.

The position offers a unique opportunity to work at the interface of fundamental and applied research, to benefit from close interactions with experts across multiple disciplines, and to contribute to innovations that can have a tangible impact on sustainable biomanufacturing.

Job requirements
We welcome applications from candidates who:

• have completed a PhD in a relevant discipline, such as molecular biology, metabolic engineering, synthetic biology or cell biology;
• enjoy experimental research and have hands-on experience in molecular biology, genetics and/or genome engineering;
• have demonstrated creativity and independence in experimental research and are keen to develop and implement innovative methodologies
• appreciate the value of close interaction with an industrial partner and are motivated by research with real-world impact;
• have excellent oral and written communication skills in English;
• contribute to a respectful, inclusive, collaborative and ambitious research environment.

TU Delft (Delft University of Technology)
Working at TU Delft means contributing to solutions that really make a difference.

For over 180 years, we have been training engineers who make an impact worldwide in companies, government bodies, or as entrepreneurs. Our alumni turn knowledge into concrete solutions for the challenges of today and tomorrow. These challenges are changing rapidly. That is why we focus on themes such as energy, climate, digitalisation, artificial intelligence (AI), and smart mobility every day. Our education and research are directly aligned with what society needs now and in the future.

At TU Delft, our people make the difference. With their knowledge and curiosity, our staff provide a high-quality education and conduct pioneering research that extends beyond the campus. You will have the opportunity to take the initiative, work with others, and grow as a professional. Working at TU Delft means join an international community of professionals and students. Together, we create knowledge, innovations, and solutions that help move the world forward.

Faculty Applied Sciences
With more than 1,100 employees, including 150 pioneering principal investigators, as well as a population of about 3,600 passionate students, the Faculty of Applied Sciences is an inspiring scientific ecosystem. Focusing on key enabling technologies, such as quantum- and nanotechnology, photonics, biotechnology, synthetic biology and materials for energy storage and conversion, our faculty aims to provide solutions to important problems of the 21st century. To that end, we educate innovative students in broad Bachelor's and specialist Master's programmes with a strong research component. Our scientists conduct ground-breaking fundamental and applied research in the fields of Life and Health Science & Technology, Nanoscience, Chemical Engineering, Radiation Science & Technology, and Engineering Physics. We are also training the next generation of high school teachers.

Click here to go to the website of the Faculty of Applied Sciences.

PhD Position in Single-Molecule Biophysic

Job description

We are looking for a PhD student passionate about understanding molecular mechanisms in biological systems. This position involves applying single-molecule techniques to study molecular interactions, including protein-ligand interactions and protein-peptide interactions. The candidate will work in an interdisciplinary environment, combining experimental approaches (single molecule fluorescence and biochemistry) with computational methods. The candidate will obtain single-molecule multiplexing data and validate machine learning predictions using the high-throughput data. The successful candidate will collaborate with international partners for therapeutic applications of this research. The project offers opportunities to make significant contributions to understanding molecular interactions and their implications for both fundamental and medical sciences.

Job requirements

• MSc degree (or nearing completion) in physics, biophysics, computational biology, or a related field.
• Strong programming skills (Python) and experience in data analysis and computational methods.
• Familiarity with molecular biology techniques.
• Excellent written and spoken English skills.
• Ability to work effectively in a collaborative, international, and interdisciplinary environment.

This position is part of a Marie Skłodowska-Curie Doctoral Network. Applicants must satisfy the MSCA mobility rule: at the time of recruitment, they must not have lived or carried out their main activity, such as work or study, in the Netherlands for more than 12 months during the previous 36 months. The rule applies regardless of nationality.

TU Delft (Delft University of Technology)
Working at TU Delft means contributing to solutions that really make a difference.

For over 180 years, we have been training engineers who make an impact worldwide in companies, government bodies, or as entrepreneurs. Our alumni turn knowledge into concrete solutions for the challenges of today and tomorrow.

These challenges are changing rapidly. That is why we focus on themes such as energy, climate, digitalisation, artificial intelligence (AI), and smart mobility every day. Our education and research are directly aligned with what society needs now and in the future.

At TU Delft, our people make the difference. With their knowledge and curiosity, our staff provide a high-quality education and conduct pioneering research that extends beyond the campus. You will have the opportunity to take the initiative, work with others, and grow as a professional.

Working at TU Delft means join an international community of professionals and students. Together, we create knowledge, innovations, and solutions that help move the world forward.

Faculty Applied Sciences
With more than 1,100 employees, including 150 pioneering principal investigators, as well as a population of about 3,600 passionate students, the Faculty of Applied Sciences is an inspiring scientific ecosystem. Focusing on key enabling technologies, such as quantum- and nanotechnology, photonics, biotechnology, synthetic biology and materials for energy storage and conversion, our faculty aims to provide solutions to important problems of the 21st century. To that end, we educate innovative students in broad Bachelor's and specialist Master's programmes with a strong research component. Our scientists conduct ground-breaking fundamental and applied research in the fields of Life and Health Science & Technology, Nanoscience, Chemical Engineering, Radiation Science & Technology, and Engineering Physics. We are also training the next generation of high school teachers.

Click here to go to the website of the Faculty of Applied Sciences.

Postdoc Understanding and Improving Robustness of Yeast in an Industrial Process

Job description

You will join a vibrant and collaborative research environment within the Industrial Microbiology section of the Department of Biotechnology at TU Delft. The section brings together six principal investigators and a diverse international team of postdoctoral researchers, PhD candidates and technicians with complementary expertise in modelling, molecular biology, genomics, microbial physiology, synthetic biology and metabolic engineering. This multidisciplinary environment provides excellent opportunities for scientific exchange and collaboration.

This project, co-supervised by professors Jack Pronk and Jean-Marc Daran, is conducted in close collaboration with a leading biotechnology company. It focuses on understanding the molecular basis of a key robustness trait in a yeast-based production process that is already deployed at industrial scale. This unique setting offers an excellent opportunity to address fundamental questions in microbial physiology while working on a challenge of direct relevance to industrial biotechnology.

The successful candidate will investigate the cellular and molecular mechanisms underlying robustness in industrial yeast strains and translate this knowledge into rational strategies for strain improvement. The project will combine cell biology, genome editing and quantitative physiological studies in laboratory bioreactors.

The position offers a unique opportunity to work at the interface of fundamental and applied research, to benefit from close interactions with experts across multiple disciplines, and to contribute to innovations that can have a tangible impact on sustainable biomanufacturing.

Job requirements
We welcome applications from candidates who:

• have completed a PhD in a relevant discipline, such as molecular biology, metabolic engineering, synthetic biology or cell biology;
• enjoy experimental research and have hands-on experience in molecular biology, genetics and/or genome engineering;
• have demonstrated creativity and independence in experimental research and are keen to develop and implement innovative methodologies
• appreciate the value of close interaction with an industrial partner and are motivated by research with real-world impact;
• have excellent oral and written communication skills in English;
• contribute to a respectful, inclusive, collaborative and ambitious research environment.

TU Delft (Delft University of Technology)
Working at TU Delft means contributing to solutions that really make a difference.

For over 180 years, we have been training engineers who make an impact worldwide in companies, government bodies, or as entrepreneurs. Our alumni turn knowledge into concrete solutions for the challenges of today and tomorrow. These challenges are changing rapidly. That is why we focus on themes such as energy, climate, digitalisation, artificial intelligence (AI), and smart mobility every day. Our education and research are directly aligned with what society needs now and in the future.

At TU Delft, our people make the difference. With their knowledge and curiosity, our staff provide a high-quality education and conduct pioneering research that extends beyond the campus. You will have the opportunity to take the initiative, work with others, and grow as a professional. Working at TU Delft means join an international community of professionals and students. Together, we create knowledge, innovations, and solutions that help move the world forward.

Faculty Applied Sciences
With more than 1,100 employees, including 150 pioneering principal investigators, as well as a population of about 3,600 passionate students, the Faculty of Applied Sciences is an inspiring scientific ecosystem. Focusing on key enabling technologies, such as quantum- and nanotechnology, photonics, biotechnology, synthetic biology and materials for energy storage and conversion, our faculty aims to provide solutions to important problems of the 21st century. To that end, we educate innovative students in broad Bachelor's and specialist Master's programmes with a strong research component. Our scientists conduct ground-breaking fundamental and applied research in the fields of Life and Health Science & Technology, Nanoscience, Chemical Engineering, Radiation Science & Technology, and Engineering Physics. We are also training the next generation of high school teachers.

Click here to go to the website of the Faculty of Applied Sciences.

Assistant/Associate Professor in Visual Analytics

Job description

The Computer Graphics and Visualization group at TU Delft has an opening for an Assistant/Associate Professor in Visual Analytics. We seek a researcher with an ambitious research agenda in visual analytics and interactive data exploration, spanning areas such as human-AI interaction, explainable AI, decision support, and data-driven discovery. Our group develops computational methods and theory for generating, analyzing, and interacting with visual data. Our research spans computer graphics, visualization, rendering, modeling, interaction, simulation, game technology, and immersive environments, with strong connections to artificial intelligence, data science, AR/VR, 3D computer vision, and high-performance computing. We foster a multidisciplinary research environment that combines fundamental advances with impactful applications across a wide range of domains.

We particularly welcome candidates whose research advances visual analytics for the interactive exploration, analysis, and interpretation of complex data, including approaches that integrate human-centered artificial intelligence to support understanding and decision-making. Working within a supportive department that values scientific excellence, creativity, and complementary expertise, you will collaborate across disciplines, contribute to leading international venues, and help shape an ambitious research agenda. A key part of the role is developing an independent and internationally visible research programme in visual analytics. You will identify emerging scientific opportunities, translate them into innovative research projects, acquire and lead externally funded research, and build collaborations with academic, public-sector, and industry partners. Through your work, you will contribute to scientific advances and address challenges in domains where human understanding of complex data is essential, such as healthcare, engineering, sustainability, science, and public policy.

You will work with a highly talented and international student population, including students from our MSc programmes in Computer Science and Data Science & Artificial Intelligence Technology, and our BSc programme in Computer Science and Engineering. You will contribute to teaching and developing courses in visual analytics and related topics, creating an engaging and inclusive learning environment that inspires students from diverse backgrounds. You will supervise and mentor BSc, MSc, and PhD students, supporting their development into independent researchers and highly skilled professionals. As your research programme grows, you will have the opportunity to build and lead your own research team. TU Delft offers excellent opportunities for professional development, interdisciplinary collaboration, and access to state-of-the-art research facilities. Through your research, teaching, and leadership, you will help shape the future of visual analytics while educating the next generation of experts in data science, artificial intelligence, and visual computing.

Job requirements

• You hold a PhD in Computer Science, Mathematics, Physics, Electrical Engineering, Data Science, Artificial Intelligence, or a closely related discipline.
• You have a strong research record and a clear vision for future research in visual analytics or related fields.
• You are enthusiastic about teaching and developing courses in visual analytics and related computer science topics.
• You communicate effectively in English and contribute to an international, collaborative, and inclusive academic environment.
• You have the potential to develop, or have already demonstrated, an independent and internationally visible research programme.
• You are motivated to develop collaborations with academic, industrial, and societal partners.
• You have experience with, or strong potential for, acquiring competitive external research funding.
• You have experience supervising students and researchers, or clear potential to do so.
• For appointment at the Associate Professor level, you demonstrate an established independent research profile, successful funding acquisition, supervision experience, and academic leadership.

TU Delft (Delft University of Technology)
Working at TU Delft means contributing to solutions that really make a difference.

For over 180 years, we have been training engineers who make an impact worldwide in companies, government bodies, or as entrepreneurs. Our alumni turn knowledge into concrete solutions for the challenges of today and tomorrow.

These challenges are changing rapidly. That is why we focus on themes such as energy, climate, digitalisation, artificial intelligence (AI), and smart mobility every day. Our education and research are directly aligned with what society needs now and in the future.

At TU Delft, our people make the difference. With their knowledge and curiosity, our staff provide a high-quality education and conduct pioneering research that extends beyond the campus. You will have the opportunity to take the initiative, work with others, and grow as a professional.

Working at TU Delft means join an international community of professionals and students. Together, we create knowledge, innovations, and solutions that help move the world forward.

Faculty of Electrical Engineering, Mathematics and Computer Science
The Faculty of Electrical Engineering, Mathematics and Computer Science (EEMCS) brings together three scientific disciplines. Combined, they reinforce each other and are the driving force behind the technology we all use in our daily lives. Technology such as the electricity grid, which our faculty is helping to make completely sustainable and future-proof. At the same time, we are developing the chips and sensors of the future, whilst also setting the foundations for the software technologies to run on this new generation of equipment – which of course includes AI. Meanwhile we are pushing the limits of applied mathematics, for example mapping out disease processes using single cell data, and using mathematics to simulate gigantic ash plumes after a volcanic eruption. In other words: there is plenty of room at the faculty for ground-breaking research. We educate innovative engineers and have excellent labs and facilities that underline our strong international position. In total, more than 1000 employees and 4,000 students work and study in this innovative environment.

Click here to go to the website of the Faculty of Electrical Engineering, Mathematics and Computer Science.