Senior medewerker Project Control voor minimaal 32 uur (4 dagen) per week

Work Activities
De voor jou belangrijkste taken en verantwoordelijkheden zijn:

• Het opstellen van (complexe) periodieke management- en/of projectrapportages en het bespreken hiervan met leidinggevende en hierover adviseren;
• Het adviseren van onderzoekers en management bij subsidieaanvragen en -toekenningen ten aanzien van financiële aspecten;
• Het signaleren van overbesteding/onderbesteding en projectrisico’s en het adviseren hierover aan de projectleider, het Hoofd Financiën en de Instituutsmanager;
• Het samen met de afdeling verzorgen van de projectadministratie;
• Deelnemen aan de jaarlijkse planning & control gesprekken met de projectleiders,
• Bijdragen aan het opstellen van de jaarrekening.

Qualifications
De ideale kandidaat voor deze functie beschikt over de volgende eigenschappen:

• Een HBO+ denk- en werkniveau;
• Een opleiding op bedrijfskundig of financieel-administratief gebied;
• Ervaring met Microsoft Office en ERP-software, bij voorkeur Unit4-ERP;
• Kennis van administratieve organisatie en subsidievoorwaarden;
• Cijfermatig inzicht en accuratesse;
• Een proactieve instelling.
• (Probleem-)analytisch vermogen;
• Kan zowel in teamverband als zelfstandig werken.

Work environment
AMOLF verricht fundamenteel onderzoek naar de fysica van complexe materie en creëert nieuwe functionele materialen, in samenwerking met universiteiten en industrie. Zie ook www.amolf.nl.

Het Advanced Research Center for Nanolithography (ARCNL) verricht fundamenteel onderzoek aan de fysica en technologie van nanolithografie, in het bijzonder voor toepassing in de halfgeleiderindustrie. ARCNL is een publiek-private samenwerking tussen ASML en meerdere kennisinstellingen. Zie ook www.arcnl.nl.

De afdeling, bestaande uit twee ervaren medewerkers, is nauw betrokken bij de inrichting én uitvoering van project control; dit omvat het ontwikkelen, inrichten, beheren en bewaken van de structuur en werking van projecten en de bijbehorende (financiële) processen. Project control adviseert de projectleiders over de (financiële) voortgang van het project en draagt zorg dat er voldaan wordt aan subsidie voorwaarden, procedures en relevante wet- en regelgeving.

Working conditions
De sfeer op het Instituut wordt in hoge mate bepaald door jonge, enthousiaste medewerkers. De communicatie is informeel en de lijnen zijn kort.Onze uitstekende secundaire arbeidsvoorwaarden zijn hier te raadplegen. Interne training en studiefaciliteiten zijn vanzelfsprekend. Inschaling vindt, afhankelijk van relevante kennis en ervaring, plaats in NWO-I CAO schaal 9/10; maximaal € 5.486 bruto per maand exclusief vakantiegeld (8%) en eindejaarsuitkering (8,33%). De functie is voor 0.8-1 fte. We bieden een dienstverband van twee jaar, met de intentie van aansluitend een vast dienstverband.

Voor aanstelling in deze functie is een ‘Verklaring Omtrent het Gedrag’ vereist. De aanvraagkosten worden door AMOLF vergoed.

More information?
Voor nadere inlichtingen over de inhoud van de functie kun je je wenden tot Jeroen Weijers via j.weijers@amolf.nl

Application
Lijkt deze baan iets voor jou? Reageer dan via de onderstaande knop!

Online screening kan deel uitmaken van de selectieprocedure.

Diversity code
AMOLF and ARCNL are highly committed to an inclusive and diverse work environment: we want to develop talent and creativity by bringing together people from different backgrounds and cultures. We recruit and select on the basis of competencies and talents. We strongly encourage anyone with the right qualifications to apply for the vacancy, regardless of age, gender, origin, sexual orientation or physical ability.

Commercial activities in response to this ad are not appreciated.

Director of the NWO-Institute AMOLF

Work Activities
The director of AMOLF is a recognised scientist with a strong international reputation, a passion and vision for the main research directions of AMOLF, and a strong interest in leading a research organisation. It is common to combine the directorship position with heading an active research group at the institute.

As director of AMOLF, you lead AMOLF’s scientific and support staff in an engaging manner, with a keen eye for potential future directions, and a vision for the position of AMOLF within the Dutch research landscape. You are also responsible for initiating contacts and collaborations with industrial, societal, and academic partners. As AMOLF is one of NWO’s ten research institutes, the director is also a member of the collegial team of institute directors in order to align a common agenda for the whole organization.

Responsibilities & Key Challenges

1. As director, you maintain the institute’s excellent scientific quality, foster the existing research themes and identify new cross-disciplinary research directions and opportunities for collaboration with industry.
2. You are responsible for leading the institute, in close collaboration with the management team consisting of the director, institute manager and the three department heads.
3. You foster relationships with Dutch universities and other national and international partners in science, industry, and society, and proactively engage AMOLF in research consortia and funding opportunities.
4. You are the primary representative of AMOLF and actively advocate the interest of the institute in a dynamic external environment.
5. You are responsible for the institute’s staff recruitment and talent development.
6. You create a diverse and safe working environment, fostering a collaborative and stimulating atmosphere. You act as a role model for these qualities.
7. The AMOLF director is accountable to the chair of the Board of the NWO Institute organization and reports to the Board concerning AMOLF’s scientific strategy and mission.

Qualifications
As a director of AMOLF, you bring:

• Capacity to develop the institute’s scientific and organisational strategy with a clear vision, and to translate this strategy into concrete actions.
• Experience in building a high-performance team of professionals.
• Proven management experience.
• Ability to engage in national and international scientific consortia and to secure funding. Interest in developing opportunities for industrial collaborations, and building a strong external network, including governmental and societal partners.
• Commitment to an empathetic and inclusive leadership style that allows employees at all levels to develop optimally, resulting in an inspiring and collaborative working environment. This environment is nurtured by personal interactions, for which a strong presence is essential.
• Capacity to clearly explain complex messages, and enthusiasm for open communication both within and outside the institute.
• Familiarity with the Dutch and European system of scientific research and the relevant political structures.

Work environment
AMOLF is the national research institute for the physics of functional complex matter in the Netherlands. AMOLF’s mission is to initiate and perform leading fundamental research on the physics of complex forms of matter, and to create new functional materials. We do this in partnership with academia and industry, providing solutions to societal challenges. AMOLF is one of ten research institutes under the umbrella of the Dutch Research Council (as NWO-I, Foundation for Dutch Scientific Research Institutes), and is located at Amsterdam Science Park.

AMOLF regularly renews its scientific programme with the aim of serving as an incubator for new cross-disciplinary research directions, encompassing physics, chemistry, biology, and engineering. The current research themes are Sustainable Energy Materials, Information in Matter, and Autonomous Matter. In 2023 a strategic plan for the next six years has been laid out (see the AMOLF website).

With a yearly budget of around €25 million, AMOLF hosts 19 research groups and has 250 employees, including about 70 PhD students and 30 postdocs. It is a flat and informal organisation committed to internal collaboration and sharing infrastructure between groups. AMOLF shares its support staff, which consists of about 50 technicians with a wide variety of expertise and 35 administrative support staff, with another NWO-institute ARCNL (Advanced Research Center for Nanolithography). About a third of the research projects are performed in collaboration with industrial partners. The base funding from NWO covers the costs of infrastructure, support staff and the tenured staff. Junior research positions and material budgets are funded by external grants, earned in national and international competition, and by collaborative contracts with industry.

Working conditions
We offer a contract for 40 hours per week. NWO-I will employ you on a tenured appointment with an initial commission as AMOLF director for a five-year term, after which reappointment can take place for another term. After that, it is possible to continue working within NWO-I in a different position. AMOLF can support the transition of your research group to the institute.

The gross monthly salary -dependent on experience- ranges from €9,526 to €12,644 (scale 18 in the Dutch Collective Labour Agreement for Research Institutes), with an additional 8% holiday allowance and 8.33% year-end bonus.

NWO-I offers a flexible set of secondary employee benefits, including both retirement and work disability pensions through the national Civil Pension Fund ABP. If accepting this position requires your partner to find new employment, we can offer assistance.

More information?
More information on AMOLF can be found on the AMOLF website.

For further information about the position, you can approach AMOLF management team member prof.dr. Sander Tans (s.tans@amolf.nl) and AMOLF’s institute manager dr. Paula van Tijn (p.van.tijn@amolf.nl).

For information about the procedure Henk Tamsma, secretary to the advisory appointment committee, is available (h.tamsma@nwo-i.nl, +31 6 16049639).

Application
If you feel the profile fits you, and you are interested in the position, we look forward to receiving your application. You can apply online via the button on the page. We will accept applications up to and including 1 June 2025.

Your application should include the following information:

• A letter which addresses your working life path and how your experience contributes to the job profile
• A detailed cv
• A list of publications

The first round of interviews will be held end of June / beginning of July 2025.

A certificate of good conduct will be required in the final stage of the process. Screening (selection assessment) and online screening may be part of the procedure.

Diversity code
AMOLF is highly committed to an inclusive and diverse work environment: we want to develop talent and creativity by bringing together people from different backgrounds and cultures. We recruit and select on the basis of competencies and talents. We strongly encourage anyone with the right qualifications to apply for the vacancy, regardless of age, gender, origin, sexual orientation or physical ability.

AMOLF has won the NNV Diversity Award 2022, which is awarded every two years by the Netherlands Physical Society for demonstrating the most successful implementation of equality, diversity and inclusion (EDI).

Commercial activities in response to this ad are not appreciated.

PhD position: biophysics of cellular time-keeping during animal development

Work Activities
In this project, you will use advanced microscopy and quantitative analysis to solve an important fundamental question: how cells in embryos keep track of time, to execute their functions at exactly the right stage of development. You will address this question in the nematode worm C. elegans. Using a quantitative, physics-inspired approach, you will measure the dynamics of molecules that function as timing regulators in growing and developing animals, to reveal how these molecules encode time with high accuracy. You will work in an enthusiastic and diverse group of PhD student and postdocs with backgrounds in physics and quantitative biology at the AMOLF institute in Amsterdam, and in close collaboration with research groups at the Hubrecht Institute, TU Delft and ENS Paris.

Background. During development from embryo to adult, a mindboggling multitude of processes unfolds with highly intricate timing, with failure to start and stop these processes at the correct time giving rise to lethality, malformations and disease. Yet, how cells measure time, to execute each process at exactly the right stage and for the correct duration, remains one of the biggest unsolved mysteries in biology. Information on time is likely encoded in the dynamics of specific timing proteins, whose concentrations rise, fall or oscillate within individual cells during development. In this picture, a cell deduces time simply by measuring the current concentration of timing proteins within the cells. However, this mechanism gives rise to many important unresolved questions. How can cells measure timing protein level accurately, despite the strong random variability in molecular dynamics that is inherent to cells? Can cells make more accurate measurements of time by combining concentration measurements of multiple timing proteins, each with their own dynamics? What molecular mechanisms do cells use to measure timing protein levels and can these be optimized to extract as much time information as possible? The comparative simplicity of C. elegans development combined with our group’s unique quantitative expertise will enable you to answer these questions for the first time.

Approach. You will use a unique time-lapse microscopy approach developed in our group to visualize and quantify timing protein dynamics in single C. elegans cells, while these cells undergo the precisely-timed division and differentiation events that are required for normal development. Here, you will make use of new fluorescent reporters developed by our collaborators at the Hubrecht institute, to quantify protein concentration dynamics with unparalleled sensitivity. You will develop quantitative analysis approaches to measure the time information encoded in timing protein dynamics, in collaboration with theoretical physicists at TU Delft. You will use mutants that perturb timing protein dynamics and, hence, time information, and study how this changes the cell’s division and differentiation timing, and how these changes give rise to developmental defects. You will connect your dynamics measurements to parallel experiments, performed at the Hubrecht institute, that study the action of timing protein using novel whole-genome techniques (ChIC-seq, EU-seq). In collaboration with ENS Paris, you will examine how dynamics is changed in different C. elegans isolated from the wild that show changed timing of their development.

Our group. We are a social and diverse research group, with a supportive and collaborative atmosphere. We use a quantitative, physics-inspired approach to understand how living organisms reliably build their bodies during development, focusing both on the free-living nematode C. elegans and in-vitro models such as intestinal organoids. We use advanced time-lapse microscopy (Nature Comm 2016, Elife 2022), AI-driven image analysis (PLOS ONE 2020, BioRxiv 2024), and quantitative analysis combined with mathematical models (Elife 2021, PNAS 2022, Science Advances 2023) to ultimately identify underlying molecular mechanisms.

Qualifications
We are looking for outstanding physicists and biologists with strong interest in quantitative biophysics questions, and ideally with experience in programming and handling of complex data. You should like the idea of working in a collaborative, ambitious and international environment. Excellent verbal and written English skills are essential.

Work environment
AMOLF is a part of NWO-I and initiate and performs leading fundamental research on the physics of complex forms of matter, and to create new functional materials, in partnership with academia and industry. The institute is located at Amsterdam Science Park and currently employs about 140 researchers and 80 support employees. www.amolf.nl

Working conditions

• The working atmosphere at the institute is largely determined by young, enthusiastic, mostly foreign employees. Communication is informal and runs through short lines of communication.
• The position is intended as full-time (40 hours / week, 12 months / year) appointment in the service of the Netherlands Foundation of Scientific Research Institutes (NWO-I) for the duration of four years
• The starting salary is 2.781 Euro’s gross per month and a range of employment benefits.
• After successful completion of the PhD research a PhD degree will be granted at a Dutch University.
• Several courses are offered, specially developed for PhD-students.
• AMOLF assists any new foreign PhD-student with housing and visa applications and compensates their transport costs and furnishing expenses.

More information?
For further information about the position, please contact Jeroen van Zon: j.v.zon@amolf.nl and .

Application
You can respond to this vacancy online via the button below.

Online screening may be part of the selection.

Diversity code
AMOLF is highly committed to an inclusive and diverse work environment: we want to develop talent and creativity by bringing together people from different backgrounds and cultures. We recruit and select on the basis of competencies and talents. We strongly encourage anyone with the right qualifications to apply for the vacancy, regardless of age, gender, origin, sexual orientation or physical ability.

AMOLF has won the NNV Diversity Award 2022, which is awarded every two years by the Netherlands Physical Society for demonstrating the most successful implementation of equality, diversity and inclusion (EDI).

Commercial activities in response to this ad are not appreciated.

PhD position: biophysics of cellular time-keeping during animal development

Work Activities
In this project, you will use advanced microscopy and quantitative analysis to solve an important fundamental question: how cells in embryos keep track of time, to execute their functions at exactly the right stage of development. You will address this question in the nematode worm C. elegans. Using a quantitative, physics-inspired approach, you will measure the dynamics of molecules that function as timing regulators in growing and developing animals, to reveal how these molecules encode time with high accuracy. You will work in an enthusiastic and diverse group of PhD student and postdocs with backgrounds in physics and quantitative biology at the AMOLF institute in Amsterdam, and in close collaboration with research groups at the Hubrecht Institute, TU Delft and ENS Paris.

Background. During development from embryo to adult, a mindboggling multitude of processes unfolds with highly intricate timing, with failure to start and stop these processes at the correct time giving rise to lethality, malformations and disease. Yet, how cells measure time, to execute each process at exactly the right stage and for the correct duration, remains one of the biggest unsolved mysteries in biology. Information on time is likely encoded in the dynamics of specific timing proteins, whose concentrations rise, fall or oscillate within individual cells during development. In this picture, a cell deduces time simply by measuring the current concentration of timing proteins within the cells. However, this mechanism gives rise to many important unresolved questions. How can cells measure timing protein level accurately, despite the strong random variability in molecular dynamics that is inherent to cells? Can cells make more accurate measurements of time by combining concentration measurements of multiple timing proteins, each with their own dynamics? What molecular mechanisms do cells use to measure timing protein levels and can these be optimized to extract as much time information as possible? The comparative simplicity of C. elegans development combined with our group’s unique quantitative expertise will enable you to answer these questions for the first time.

Approach. You will use a unique time-lapse microscopy approach developed in our group to visualize and quantify timing protein dynamics in single C. elegans cells, while these cells undergo the precisely-timed division and differentiation events that are required for normal development. Here, you will make use of new fluorescent reporters developed by our collaborators at the Hubrecht institute, to quantify protein concentration dynamics with unparalleled sensitivity. You will develop quantitative analysis approaches to measure the time information encoded in timing protein dynamics, in collaboration with theoretical physicists at TU Delft. You will use mutants that perturb timing protein dynamics and, hence, time information, and study how this changes the cell’s division and differentiation timing, and how these changes give rise to developmental defects. You will connect your dynamics measurements to parallel experiments, performed at the Hubrecht institute, that study the action of timing protein using novel whole-genome techniques (ChIC-seq, EU-seq). In collaboration with ENS Paris, you will examine how dynamics is changed in different C. elegans isolated from the wild that show changed timing of their development.

Our group. We are a social and diverse research group, with a supportive and collaborative atmosphere. We use a quantitative, physics-inspired approach to understand how living organisms reliably build their bodies during development, focusing both on the free-living nematode C. elegans and in-vitro models such as intestinal organoids. We use advanced time-lapse microscopy (Nature Comm 2016, Elife 2022), AI-driven image analysis (PLOS ONE 2020, BioRxiv 2024), and quantitative analysis combined with mathematical models (Elife 2021, PNAS 2022, Science Advances 2023) to ultimately identify underlying molecular mechanisms.

Qualifications
We are looking for outstanding physicists and biologists with strong interest in quantitative biophysics questions, and ideally with experience in programming and handling of complex data. You should like the idea of working in a collaborative, ambitious and international environment. Excellent verbal and written English skills are essential.

Work environment
AMOLF is a part of NWO-I and initiate and performs leading fundamental research on the physics of complex forms of matter, and to create new functional materials, in partnership with academia and industry. The institute is located at Amsterdam Science Park and currently employs about 140 researchers and 80 support employees. www.amolf.nl

Working conditions

• The working atmosphere at the institute is largely determined by young, enthusiastic, mostly foreign employees. Communication is informal and runs through short lines of communication.
• The position is intended as full-time (40 hours / week, 12 months / year) appointment in the service of the Netherlands Foundation of Scientific Research Institutes (NWO-I) for the duration of four years
• The starting salary is 2.781 Euro’s gross per month and a range of employment benefits.
• After successful completion of the PhD research a PhD degree will be granted at a Dutch University.
• Several courses are offered, specially developed for PhD-students.
• AMOLF assists any new foreign PhD-student with housing and visa applications and compensates their transport costs and furnishing expenses.

More information?
For further information about the position, please contact Jeroen van Zon: j.v.zon@amolf.nl and .

Application
You can respond to this vacancy online via the button below.

Online screening may be part of the selection.

Diversity code
AMOLF is highly committed to an inclusive and diverse work environment: we want to develop talent and creativity by bringing together people from different backgrounds and cultures. We recruit and select on the basis of competencies and talents. We strongly encourage anyone with the right qualifications to apply for the vacancy, regardless of age, gender, origin, sexual orientation or physical ability.

AMOLF has won the NNV Diversity Award 2022, which is awarded every two years by the Netherlands Physical Society for demonstrating the most successful implementation of equality, diversity and inclusion (EDI).

Commercial activities in response to this ad are not appreciated.

Postdoc: The single-molecule biophysics of ribosome cooperation

Work Activities
Summary - In this project, you will perform innovative (bio)physics experiments to elucidate the dynamic action of individual ribosomes. The key methodologies are optical tweezers and single-molecule fluorescence, as well as selective ribosome profiling – an exciting new RNA sequencing method. Working in the Tans biophysics lab @ AMOLF Amsterdam, you will visualize the real-time translation activity of ribosomes, how multiple ribosomes work together, detect the folding of individual polypeptide chains, and show how chaperones guide this process. You will work in an international team, with other groups specialized in ribosome profiling and cryo-EM techniques. The aim is to elucidate the fundamental mechanisms that underlie the correct and erroneous production of new proteins.

Questions - According to textbooks, ribosomes work individually to produce proteins. However, recent insights from our lab and others show multiple ribosomes cooperate as they translate mRNA. This cooperation may well be essential to produce multi-protein complexes faithfully. In our group, we aim to elucidate the highly diverse and broad implications. Questions include: Do ribosomes synchronize their translation activity in real-time, like a sequence of cars in traffic? Are mRNA secondary structures and/or direct interactions between ribosomes involved? How do the two (or more) protein chains synthesized by these multiple ribosomes fold together to form protein complexes? How many ribosomes cooperate together? Can we see cooperation between ribosomes that translate different RNA messages? Given the novelty of these fundamental questions in this rapidly expanding field, you will have a unique chance to address them first.

Approach - You will directly follow the unknown dynamics of ribosome translation, protein folding and assembly, and chaperone guidance. This is enabled using optical tweezers combined with single-molecule fluorescence, which detect changes in individual molecules at nanometer and millisecond resolution. In collaboration with our partners, you will also use selective ribosome profiling – an RNA sequencing method that provides high-level data across the genome an in-vivo. This first look may reveal a host of unexpected phenomena. You will develop new experimental schemes, Use cutting-edge single-molecule fluorescence and manipulation methods, Adapt existing biochemical protocols, Analyze the complex temporal data, formulation of new models, And explain your findings in high-level scientific papers.

International team - You will be part of a collaboration with leading groups at Heidelberg University and the ETH in Zurich, which use novel sequencing and cryo-EM methods. By working within this motivated group of young scientists, you will obtain a unique training, understanding and skill set in this expanding field. By integrating these approaches, you will provide insights of unprecedented detail, spanning from the cellular to the atomic level, from in vivo to in vitro, from genome-wide patterns to molecular mechanisms, and from bacteria to human cells.

Image left show ribosome (blue, orange) that synthesized protein chain (yellow) by translating the RNA message (red). Image right shows dynamic ribosome interactions.

Qualifications
We have a number of positions available (PhD and PD). We are looking for outstanding experimental physicists or chemists with an interest in single-molecule techniques, ambition to make breakthrough findings, programming skills to handle complex data, and who thrive in a diverse, collaborative, and supportive environment. Excellent verbal and written English skills are essential.

Work environment
AMOLF is a part of NWO-I and initiate and performs leading fundamental research on the physics of complex forms of matter, and to create new functional materials, in partnership with academia and industry. The institute is located at Amsterdam Science Park and currently employs about 140 researchers and 80 support employees. www.amolf.nl

Our group - We form a lively and close-knit research group of about 10 PhD students and postdocs, which work together in small teams on various projects in a highly supportive and social atmosphere that extends to the other research groups at the AMOLF institute, which is housed in a modern building in the east of Amsterdam. The Tans group at the AMOLF institute Amsterdam has been at the forefront of studying chaperone-guided protein folding using optical tweezers. This technique allows one to mechanically manipulate individual proteins, and hence follow the movements and folding steps as they fold. We have shown striking sequences of molecular events that underlie chaperone functions, which are invisible with other methods.

https://www.sandertanslab.nl

https://amolf.nl/research-groups/biophysics

Working conditions

• The working atmosphere at the institute is largely determined by young, enthusiastic, mostly foreign employees. Communication is informal and runs through short lines of communication.
• The position is intended as full-time (40 hours / week, 12 months / year) appointment in the service of the Netherlands Foundation of Scientific Research Institutes (NWO-I) for the duration of four years
• Funding is available to attend regularly international conferences.
• AMOLF assists any new foreign researcher with housing and visa applications and compensates their transport costs and furnishing expenses.

More information?
https://www.sandertanslab.nl

Application
You can respond to this vacancy online via the button below.

Please annex your:

• Resume;
• Motivation on why you want to join the group (max. 1 page).

It is important to us to know why you want to join our team. Hence, we will only consider your application if it contains your motivation letter.

Applications will be evaluated on a rolling basis and as soon as an excellent match is made, the position will be filled.

Online screening may be part of the selection.

Diversity code
AMOLF is highly committed to an inclusive and diverse work environment: we want to develop talent and creativity by bringing together people from different backgrounds and cultures. We recruit and select on the basis of competencies and talents. We strongly encourage anyone with the right qualifications to apply for the vacancy, regardless of age, gender, origin, sexual orientation or physical ability.

AMOLF has won the NNV Diversity Award 2022, which is awarded every two years by the Netherlands Physical Society for demonstrating the most successful implementation of equality, diversity and inclusion (EDI).

Commercial activities in response to this ad are not appreciated.